Has anyone had success treating androgenic hair loss topically?
    6/4/2026

    From the encyclopedia
    Finasteride →

    Popular 5-alpha reductase inhibitor that lowers DHT, taken as a pill or used topically

    Spironolactone →

    Blood-pressure and diuretic drug with anti-androgen effects

    Clascoterone →

    Topical androgen-receptor blocker, approved as an acne cream

    At a glance
    In this question or advice post, the primary subjects mentioned are
    💧 Finasteride (topical) 0.005%
    💧 Spironolactone (topical)
    💧 Clascoterone (topical)
    • Pumpkin seed oil (supplement)
    the tone is 😐 neutral.

    Other terms

    A woman with androgenic hair loss, likely due to PCOS, is seeking topical treatments as oral medications are not an option. Suggested treatments include topical finasteride, spironolactone, and clascoterone, with spironolactone and clascoterone being safer options due to lower systemic absorption risk.
    View this post in the Community →

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    Related research 6

    1. Androgenetic Alopecia in Women: A Narrative Review of Pathophysiology, Clinical Evaluation, and Treatments American Journal of Clinical Dermatology · 2026
    2. Antiandrogens and Androgen Inhibitors Elsevier eBooks · 2020
    3. The Hormonal Background of Hair Loss in Non-Scarring Alopecias Biomedicines · 2024
    4. Androgenetic Alopecia: update on Etiology, Pathophysiology, Diagnosis and Treatment International journal of pharmaceutical sciences and drug research · 2024
    5. A decade of progress in androgenetic alopecia management: Emerging therapies and multimodal strategies IP Indian Journal of Clinical and Experimental Dermatology · 2025
    6. SYSTEMATIC REVIEW OF PHARMACOTHERAPY STRATEGIES IN THE MANAGEMENT OF HIDRADENITIS SUPPURATIVA International Journal of Innovative Technologies in Social Science · 2025