Ovarian Surgery for Symptom Relief in Women with Polycystic Ovary Syndrome

November 2017 in “ Cochrane library ”

Sam Lepine, Junyoung Jo, Mostafa Metwally, Ying Cheong

laparoscopic ovarian drilling polycystic ovary syndrome metformin clomiphene androgenic symptoms LOD PCOS

Studysummary This study concluded that laparoscopic ovarian drilling does not clearly improve menstrual regularity or androgenic symptoms in PCOS compared to most medical treatments, but it may have fewer gastrointestinal side effects than metformin plus clomiphene.

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The document reviewed the effectiveness of laparoscopic ovarian drilling (LOD) for symptom relief in women with polycystic ovary syndrome (PCOS). It included 22 randomized controlled trials with 2,278 women, comparing LOD to medical treatments like metformin and clomiphene. The findings indicated that LOD had inconsistent effects on menstrual regularity and androgenic symptoms, with generally low-quality evidence. LOD had fewer gastrointestinal side effects compared to some medical treatments. The review highlighted the need for more high-quality research to determine the true efficacy and safety of LOD for PCOS symptom relief.

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