In this study, researchers explored ubiquitination patterns in healthy human skin and CYLD cutaneous syndrome tumors, identifying extensive ubiquitin sites and differential protein ubiquitination linked to tumor pathology, highlighting the role of ubiquitination in tissue architecture and disease mechanisms.
November 2025 in “Advanced Therapeutics” This review examines platelet-rich plasma therapy's multidisciplinary applications in regenerative medicine and discusses preparation challenges but presents no new clinical results.
November 2025 in “Journal of Rangpur Medical College” In this study from Bangladesh Medical University, researchers found strong correlations between symptoms such as oligomenorrhea and amenorrhea with bilateral polycystic ovarian morphology in women with PCOS, highlighting the link between clinical symptoms and ultrasound findings in predicting the severity of the condition.
This study analyzed the phytochemical content of two Portulaca species and found that extracts from Portulaca oleracea L. and Portulaca grandiflora H. demonstrated suitable characteristics for hair tonic formulations, meeting Indonesian National Standards for cosmetic products.
March 2025 in “Laboratory Investigation” This systematic review found that mixed epithelial and stromal tumor of the seminal vesicle (MESTSV) is characterized by abundant stromal proliferation, architectural heterogeneity, and strong immunoreactivity for ER/PR, with most being benign but warranting surveillance for possible recurrence or metastasis.
January 2025 in “Journal of Cutaneous Medicine and Surgery” In this clinical trial, adding topical calcipotriol to intralesional triamcinolone acetonide significantly increased hair regrowth efficacy in scalp alopecia areata patches compared to steroids alone, but not in beard patches, with a lower incidence of atrophy observed.
January 2025 in “BioMed Research International” This study highlights the role of abnormal DNA methylation in skin disorders such as atopic dermatitis and psoriasis, suggesting these epigenetic changes may serve as biomarkers and targets for potential treatments.
January 2025 in “Clinical Case Reports” This study reports a rare case of follicular porokeratosis in a diabetic woman, suggesting a potential association with diabetes mellitus in addition to its known presentation with keratotic papules and scalp alopecia.
January 2025 in “International Journal of Herbal Medicine” In this case study, a 27-year-old male with premature greying of hair saw significant improvement in hair whitening after ten weeks of treatment with Unani formulations, despite no family history or systemic disorder.
December 2024 in “DIET FACTOR (Journal of Nutritional & Food Sciences)” This study reports that fenugreek seed extract (Furocyst®) improved body weight, ovarian cysts, ovary size, hair growth, and menstrual regularity in women with PCOS, indicating its potential as an effective phytotherapeutic option for managing the condition.
December 2024 in “African Journal of Biomedical Research” This study reported that the combined use of dexmedetomidine and ketamine, along with peripheral nerve blocks, provided adequate sedation and analgesia with maintained hemodynamic stability in patients undergoing minor surgical procedures like split skin grafting.
August 2024 in “Journal of Clinical Medicine” This review examines quality control in preparing platelet-rich plasma, highlighting knowledge gaps in its clinical efficacy and safety, but reports no new clinical results.
May 2024 in “British journal of dermatology/British journal of dermatology, Supplement” The researchers reported increased ubiquitination of proteins such as the insulin receptor in CYLD cutaneous syndrome skin tumors, suggesting that CYLD dysfunction may affect protein secretion and signaling processes.
In this study, a case was reported where oral Minoxidil led to severe ocular complications, specifically Central Retinal Vein Occlusion and Cilioretinal Artery Occlusion, resulting in sudden vision loss which improved upon discontinuation.
January 2024 in “International Research Journal of Modernization in Engineering Technology and Science” This review suggests that combining nanotechnology with herbal components in hair cosmetics may improve the delivery and effectiveness of treatments for issues like damage, dandruff, and hair loss.
January 2024 in “International Journal of Herbal Medicine” This abstract describes the role of melanin in determining hair color and protecting against UV radiation, highlighting how its production affects hair health, growth, and vitality, with reduced production contributing to greying with age.
November 2023 in “Journal of Skin and Sexually Transmitted Diseases” In this case report, a 65-year-old woman with non-small cell lung cancer experienced scarring alopecia with papulo-pustular lesions on the scalp due to gefitinib treatment, marking it as a rare instance of gefitinib-induced erosive pustular dermatosis of the scalp.
November 2023 in “Jundishapur journal of health sciences” This case report describes three instances of severe tinea favosa transmitted by Trichophyton schoenleinii in Afghan immigrants in Iran, highlighting an emerging health concern due to its potential to re-emerge in the region among immigrant populations.
October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study constructed a comprehensive atlas of prenatal human skin, revealing that innate immune cells, such as macrophages, play a crucial role in skin morphogenesis by interacting with non-immune cells, influencing hair follicle formation and angiogenesis beyond their traditional immune functions.
September 2023 in “Journal of the American Academy of Dermatology” This study found that the incidence of major adverse cardiovascular events in patients with psoriasis, psoriatic arthritis, and axial spondyloarthritis who received Ixekizumab was low and stable over 3 to 5 years across 25 clinical trials.
This case study reports clinical improvement and complete ulcer resolution in a 29-year-old woman with ANA-negative SLE treated for segmental hyalinizing vasculitis and valvular heart disease.
July 2023 in “British journal of dermatology/British journal of dermatology, Supplement” In this study, researchers analyzed skin tumors from patients with CYLD cutaneous syndrome and found that loss of CYLD function is linked to changes in cellular signaling pathways, particularly NF-κB signaling, and leads to increased secretion of specific extracellular matrix proteins.
In this case report, a 19-year-old woman with systemic lupus erythematosus experienced significant improvement in neuropsychiatric symptoms, including psychosis and seizures, following treatment with high-dose corticosteroids, immunosuppressants, and antidepressants.
June 2023 in “British Journal of Dermatology” This study reports a unique case of coinheritance of BRCA2 and CYLD pathogenic variants in a man with metastatic malignant cylindroma, suggesting that recognizing such genetic profiles in rare conditions can provide new treatment options, including the potential use of therapies targeting BRCA deficiency.
February 2023 in “Laboratory Animal Research” This study found that Cudrania tricuspidata and Sargassum fusiforme extracts significantly increased hair growth and related gene activity in C57BL/6 mice, suggesting potential use in alopecia treatment.
January 2023 in “TNOA journal of ophthalmic science and research” In this case report, a young male developed acute central serous chorioretinopathy after using 5% topical minoxidil for androgenic alopecia, which resolved after discontinuation of the drug and focal laser treatment.
January 2023 in “Journal of Survey in Fisheries Sciences” This study found that a polyherbal hair repair oil significantly increased hair growth and demonstrated promising efficacy and safety compared to other oils in a rat model.
August 2022 in “Gene Reports” This review discusses androgenetic alopecia and alopecia areata through a systems biology perspective using omics technologies to explore molecular mechanisms and potential personalized therapies, and it reports no new clinical results.
June 2022 in “Indian journal of clinical and experimental opthalmology” This case report details the ocular complications of Hutchinson-Gilford Progeria syndrome in a 20-year-old Bangladeshi patient, highlighting symptoms like dry eyes, Meibomian gland dysfunction, and cataracts.
June 2022 in “Authorea (Authorea)” This review discusses various methods for delivering CRISPR/Cas9 for gene editing in vitro and in vivo, highlighting delivery as a major challenge but reports no new experimental results.