Extensive Spiculated Follicular Porokeratosis With Alopecia: A Case Report

January 2025 in “ Clinical Case Reports ”

mitra abdolvand, Roya Radanfar, Mozhdeh Sepaskhah, Fatemeh Sari Aslani, Mojgan Akbarzadeh‐Jahromi

follicular porokeratosis alopecia keratotic papules spicules isotretinoin tacrolimus scarring alopecia dermoscopy histopathological examination Accutane Protopic

TLDR Follicular porokeratosis may be linked to diabetes and can lead to hair loss.

This case report details a 35-year-old woman with extensive follicular porokeratosis (FPK) leading to alopecia, associated with type 2 diabetes mellitus. FPK, a rare condition characterized by keratotic papules and spicules, was confirmed through dermoscopy and histopathological examination. Despite treatment with oral isotretinoin and topical tacrolimus, the progression to scarring alopecia was not prevented. The report underscores the potential link between FPK and diabetes and suggests that FPK should be considered in differential diagnoses of keratotic papules and alopecia.

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