Comparing the Efficacy of Combined Intralesional Triamcinolone Acetonide With Topical Calcipotriol Versus Intralesional Triamcinolone Acetonide Monotherapy in Scalp and Beard Alopecia Areata: Results From a Randomized Single-Blinded Clinical Trial

    Thoyyib Parammal Karat, Anupama Bains, Abhishek Bhardwaj, Saurabh Singh, Anil Budania, Suman Patra, Bandhala Rajan M
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    This study compared the efficacy of combined intralesional triamcinolone acetonide with topical calcipotriol versus intralesional triamcinolone acetonide monotherapy in treating alopecia areata (AA) on the scalp and beard. Conducted with 73 patients (179 patches), both treatment groups showed significant hair regrowth from the fourth week onward. However, no significant difference in terminal hair density was observed between the two groups overall. Subgroup analysis revealed that the combination treatment was more effective for scalp patches by the 12th week (P = .018) but not for beard patches. The combination treatment also resulted in more irritation but a lower incidence of atrophy compared to monotherapy.
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