The Healing Potential Of Platelet-Rich Plasma: Advances In Preparation Methods, Biomedical Applications, And Emerging Challenges

November 2025 in “ Advanced Therapeutics ”

Mustafijur Rahman, Md Golam Nur, Tanvir Mahady Dip, Nusrat Binta Hossain, Rajiv Padhye, Shadi Houshyar

platelet-rich plasma PRP growth factors cytokines regenerative medicine tissue repair

Platelet-rich plasma (PRP) is a regenerative medicine technique that enhances tissue repair by delivering concentrated platelets with growth factors and cytokines. It has applications in fields like dermatology, neurology, orthopedics, and dentistry. Despite its potential, PRP therapy faces challenges due to inconsistent preparation methods, affecting its standardization and efficacy. This review provides a multidisciplinary overview of recent advancements in PRP preparation and discusses issues like standardization and ethical considerations, aiming to improve clinical outcomes and expand PRP's therapeutic use.

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