5 citations
,
September 2024 in “Dermatological Reviews” This study reviews international perspectives on using platelet-rich plasma, stem cells, and exosomes, highlighting their expanding applications in fields like oncology, dermatology, neurology, and rheumatology, with an emphasis on ethical considerations and the need for further research.
February 2024 in “Dermatologic Surgery” This review discusses the evidence for platelet-rich plasma in hair restoration and skin rejuvenation, highlighting its benefits but noting a lack of consensus on best practices and protocols.
16 citations
,
August 2023 in “Tissue Engineering and Regenerative Medicine” 
August 2023 in “Aesthetic Plastic Surgery” This meta-analysis found that PRP monotherapy improved hair density in androgenetic alopecia patients but did not affect hair diameter, with stronger effects observed in male subjects.
21 citations
,
February 2023 in “Bioengineering” This review outlines current European legislation and manufacturing standards for platelet-rich plasma (PRP) products and provides guidance for clinicians implementing autologous PRP treatments, without reporting new clinical results.
February 2023 in “International Journal of Biological Macromolecules” This study reports that PRP-loaded bioactive fibrous hydrogels significantly enhance wound healing in diabetic foot ulcers by reducing inflammation and promoting tissue growth, with reduced administration frequency compared to standard PRP gel.
January 2023 in “Aesthetic Plastic Surgery” This study found that platelet-rich plasma treatments improved quality of life for patients with pattern hair loss, as measured by decreased HAIRDEX scores in several domains over 3-5 months.
60 citations
,
December 2021 in “Cytokine & growth factor reviews” This review discusses the regenerative applications of platelet-rich plasma across various medical fields and reports no new clinical results, highlighting the need for further research into standardizing its preparation and use.
July 2021 in “Medical journal, Armed Forces India” This study reported that using platelet-rich plasma as an intraoperative holding solution significantly improved hair density and follicular growth in hair restoration surgery for androgenetic alopecia.
17 citations
,
March 2021 in “Expert Opinion on Biological Therapy” This review analyzes the impact of different preparation methods for platelet-rich plasma, human follicles stem cells, and adipose-derived stem cells on hair regrowth and wound healing, but reports no new results; the authors emphasize convincing evidence of positive outcomes despite protocol variability.
24 citations
,
January 2021 in “Dermatologic Therapy” This review found that platelet-rich plasma therapy improved hair growth and thickness in most studies on alopecia, with the highest improvement seen when combined with Minoxidil.
72 citations
,
November 2020 in “Frontiers in Surgery” This review found that the clinical results of L-PRF as a grafting material in maxillary sinus augmentation were mixed, with some studies reporting positive effects and others finding no significant impact.
848 citations
,
October 2020 in “International Journal of Molecular Sciences” This review discusses the potential of platelet-rich plasma applications in regenerative medicine and explores recent progress and challenges in translating non-clinical PRP findings into human treatments, but reports no new clinical results.
115 citations
,
August 2020 in “International Journal of Molecular Sciences” This systematic review indicates that a platelet-rich plasma concentration of 1.0 × 10^6 plt/μL may be optimal for tissue regeneration due to sufficient nutrition supply and effective growth factor diffusion in vivo.
58 citations
,
January 2020 in “International Journal of Molecular Sciences” This review evaluates various kits for isolating platelet-rich plasma using established processing standards and finds they enable compliance with consensus quality criteria; ongoing research is needed to refine these procedures for improved consistency and safety.
169 citations
,
January 2020 in “Burns & Trauma” In this study, autologous platelet-rich plasma improved skin wound healing in mice, associated with reduced inflammation and enhanced angiogenesis and re-epithelialization, but the underlying regulatory mechanism requires further investigation.
9 citations
,
July 2019 in “Journal of cosmetic dermatology” This pilot study suggests that topical PRP may improve facial rejuvenation, with observed enhancements in collagen production and skin architecture over 8 weeks.
69 citations
,
April 2019 in “Biomedicines” This study found that hair thickness and density increased after treatment with human follicle mesenchymal stem cells and platelet rich plasma, associated with enhanced Wnt signaling and platelet derived growth factors.
33 citations
,
February 2019 in “Journal of Tissue Engineering and Regenerative Medicine” This review discusses the use of platelet-rich plasma for various dermatological conditions and highlights the need for more research to standardize its protocols and understand its biological mechanisms.
87 citations
,
February 2019 in “Tissue Engineering Part B Reviews” This review discusses the antibacterial properties of platelet-rich plasma (PRP) and summarizes existing preclinical and clinical research on its use for preventing and treating wound and bone infections, but presents no novel data.
46 citations
,
May 2018 in “Dermatologic Surgery” In this study, subdermal platelet-rich plasma injections significantly increased hair count and shaft caliber in individuals with androgenetic alopecia, with monthly treatments potentially offering greater benefits.
