TLDR Topical PRP cream may improve facial skin by boosting collagen.
The pilot study investigated the use of autologous platelet-rich plasma (PRP) in a topical cream for facial rejuvenation with 20 participants aged 30-60 over 8 weeks. Results showed qualitative improvements in skin texture, elasticity, and overall appearance, with a 2.34-fold increase in collagen gene upregulation in the PRP-treated group. Participants reported high satisfaction, and no significant adverse effects were observed. The study suggested that PRP in a topical formulation could be a promising non-invasive option for facial rejuvenation, though larger studies were needed to confirm these results.
51 citations,
November 2018 in “JAMA Dermatology” PRP injections may improve skin texture and wrinkles based on patient feedback, despite no significant changes seen by dermatologists.
348 citations,
July 2017 in “Skin appendage disorders” Platelet-rich plasma shows promise for skin and hair treatments but needs more research and standardization.
66 citations,
June 2015 in “Aesthetic Plastic Surgery” Platelet preparations generally show positive effects on wound healing and facial rejuvenation, but more thorough research is needed to confirm their effectiveness.
270 citations,
March 2012 in “Dermatologic Surgery” Platelet-rich plasma can potentially promote hair growth by stimulating cell growth and increasing certain proteins.
Cord blood platelets may have promising future medical uses but need more research.
20 citations,
October 2018 in “Aesthetic Plastic Surgery” PRP shows promise for improving facial wrinkles, skin elasticity, and hair growth, but more research is needed to standardize its use and understand its effects.
1 citations,
June 2018 in “Advances in Cosmetic Surgery” PRP might help with hair growth and skin rejuvenation, but more research is needed to prove its effectiveness.
2 citations,
June 2022 in “Cosmoderma” Regenerative medicine shows promise for improving hair and skin but needs more research for standard use.
11 citations,
August 2018 in “Facial Plastic Surgery Clinics of North America” Adipose-derived stem cells show potential for skin rejuvenation and wound healing but require more research to overcome challenges and ensure safety.
