Pilot Study: Autologous Platelet-Rich Plasma Used in a Topical Cream for Facial Rejuvenation

The pilot study investigated the use of autologous platelet-rich plasma (PRP) in a topical cream for facial rejuvenation with 20 participants aged 30-60 over 8 weeks. Results showed qualitative improvements in skin texture, elasticity, and overall appearance, with a 2.34-fold increase in collagen gene upregulation in the PRP-treated group. Participants reported high satisfaction, and no significant adverse effects were observed. The study suggested that PRP in a topical formulation could be a promising non-invasive option for facial rejuvenation, though larger studies were needed to confirm these results.