2 citations
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October 2021 in “Egyptian Journal of Chemistry” In this study, researchers used pumpkin aqueous extract to create iron nanoparticles, finding them effective at inhibiting harmful bacteria found in burn and wound infections, as well as promoting burn healing and hair growth in a laboratory mouse model.
August 2023 in “Malaysian Journal of Medicine and Health Sciences/Malaysian journal of medicine and health sciences” This study found that aqueous extract of Pueraria mirifica, when administered to a rat model, significantly reduced prostate weight, prostatic index, and serum dihydrotestosterone levels, while also improving prostate histomorphology, suggesting its potential as an anti-BPH treatment.
January 2025 in “Nanotechnology Reviews” This study reported a green synthesis method for copper oxide nanoparticles using pumpkin seed extract, achieving significant antibacterial activity against Bacillus subtilis and moderate cytotoxic effects against certain cancer cell lines, indicating potential biomedical applications for these eco-friendly nanomaterials.
4 citations
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October 2025 in “Molecules” This study concluded that extracts from fermented pumpkin peel and pulp, processed with Lactobacillus strains and kombucha, may serve as multifunctional cosmetic ingredients, offering antioxidant protection, anti-aging, and skin regeneration benefits by demonstrating cytoprotective effects and reducing inflammatory cytokines in cell assays.
This study found that the nutraceutical product DERM decreased the pro-inflammatory cytokine IL-6 in mesenchymal stem cells under in vitro conditions.
67 citations
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February 2015 in “Life Sciences” This review discusses phytotherapy options for managing benign prostatic hyperplasia, noting some herbal agents show promise in trials for mild-moderate symptoms but more evidence is needed for others.
January 2019 in “International Journal of Herbal Medicine” This study concluded that a hair emulgel formulation combining extracts from four medicinal plants demonstrated desirable characteristics of spreadability, viscosity, pH, and safety, making it effective, harmless, and economical for potential hair care use.
6 citations
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April 2025 in “Frontiers in Sustainable Food Systems” This review highlights the potential of valorizing vegetable waste by extracting valuable biomolecules for use in food, nutraceuticals, and energy, noting that while promising methods exist, several niche areas lack sufficient research on a global scale.
54 citations
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May 2017 in “Biomedicine & Pharmacotherapy” This review discusses the nutrient profile and potential health benefits of pumpkin and watermelon seeds, concluding they are underutilized and could be developed into various nutraceuticals.
1 citations
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August 2025 in “Seeds” This review examines the potential of Cucurbitaceae seeds, such as those from watermelon, melon, and pumpkin, as sustainable and innovative ingredients in cosmetics, highlighting their rich bioactive composition and benefits for skin and hair, despite challenges like environmental instability and low permeability.
This study found that vinegar-processed black soybean and its extract accelerated hair growth and prevented alopecia in mice, with potential mechanisms involving modulation of the Wnt/β-catenin signaling pathway, suggesting they may be promising functional foods for hair regeneration.
13 citations
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February 2019 in “Journal of Microencapsulation” This study focused on designing a niosome formulation that encapsulates pumpkin seed oil for topical use, achieving high entrapment efficiency and stability over three months.
June 2023 in “Journal of Ayurvedic and herbal medicine” This review article highlights the potential health benefits and pharmaceutical components of pumpkin seeds, which contain proteins, antioxidants, and essential nutrients, and discusses their traditional medicinal uses and emerging applications in the food industry.
125 citations
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December 2016 in “Molecules” This review discusses the extraction, purification, modification, and biological activity of polysaccharides from Traditional Chinese Medicine and reports no new research findings.
This study suggests that 9-Octadecenoic acid (Z)-, 2,3-dihydroxypropyl ester from African Yam bean seeds may inhibit the human 5α-reductase II enzyme, potentially helping manage BPH, although further studies are needed.
1 citations
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January 2018 in “AUSTRALIAN JOURNAL OF BASIC AND APPLIED SCIENCES” In this study, the ethanol extract of Zapoteca portoricensis stem significantly reduced markers of testosterone-induced benign prostate hyperplasia in male albino rats without harming liver and kidney function.
October 2025 in “Scientific Reports” This study found that the extracts of Serenoa repens, when evaluated through chemical, biological, and in silico methods, demonstrated anti-inflammatory, pro-apoptotic, and anti-androgenic activities against prostate cancer cell lines, suggesting potential therapeutic benefits and directing future pharmaceutical development.
2 citations
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January 2022 in “Journal of Oleo Science” This study found that oil from CG17 garden cress seeds had higher amounts of β-carotenoids, tocopherols, and vitamins compared to other genotypes, with varying physiochemical properties across all seeds.
November 2025 in “Frontiers in Pharmacology” This mini-review examines ethnopharmacological approaches to manage hair loss in postmenopausal women, highlighting promising botanical remedies like saw palmetto, rosemary oil, and ginseng. The authors underscore a need for more interdisciplinary trials and focus on traditional remedies' multifaceted benefits, while noting gaps in menopausal-specific evidence.
15 citations
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May 2022 in “Fermentation” This study found that fermented camel milk containing 50% pumpkin seed milk significantly improved oxidative stress markers in rats and enhanced sensory and physicochemical properties compared to untreated groups.
7 citations
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December 2022 in “Plants” This study suggests that guava leaf extract may inhibit hair loss by downregulating genes involved in androgen synthesis, potentially offering a natural alternative for treating androgenetic alopecia.
2 citations
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March 2025 in “Industrial Crops and Products” This study found that peach kernel oil extracted via supercritical fluid extraction had higher quality and antioxidant properties than oil obtained by other methods, effectively protecting human hair follicle keratinocytes from oxidative damage.
11 citations
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April 2025 in “Pharmaceutics” In this review, researchers explore various treatment options for alopecia, focusing on nano-drug delivery systems using plant-based substances, which are potentially effective and less harmful than current treatments, while also highlighting emerging trends such as 3D bioprinting and plant extracts for future therapies.
October 2025 in “Biomedicines” This study suggests that Terminalia chebula fruit extract may promote hair growth in androgenetic alopecia by activating specific signaling pathways and inhibiting 5α-reductase, showing effectiveness comparable to finasteride.
November 2024 in “Applied Sciences” This study suggests that while some evidence indicates potential efficacy of placental products for hair growth and inhibiting hair loss, the current scientific evidence is scarce and of low quality.
10 citations
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August 2024 in “ACS Omega” This review discusses the use of nanomaterials in cosmetics, highlighting their benefits like enhanced stability and skin penetration, while also noting potential health risks and the role of natural ingredients in formulations.
1 citations
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February 2023 in “Plants” This study reported that rice bran oil from the Thai rice variety BB4CMU showed potential in promoting melanin production and inhibiting steroid 5α-reductase, suggesting a natural option for hair revitalization.
February 2024 in “Research Square (Research Square)” This study optimized the extraction process for abomasum protein from Tianshan red deer, identifying two proteins with anti-inflammatory and anti-tumor activities, suggesting they could be beneficial in foods and nutraceuticals.
8 citations
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January 2024 in “Current Research in Food Science” This study found that using composite alginate hydrogels containing Aloe vera, CMC, and tragacanth can improve the encapsulation efficiency and protect pumpkin seed protein hydrolysates from degradation during simulated gastrointestinal digestion, potentially increasing their applicability as functional food components.
3 citations
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February 2024 in “International journal of molecular sciences” This review highlights the potential of valorizing citrus by-products, particularly hesperidin from orange peels, as sustainable ingredients in skincare for antiaging, pigmentation, wound healing, and UV damage protection, emphasizing hesperidin's role in a circular economy approach.