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Inhibitors of the enzyme 5 alpha-reductase could potentially treat disorders like prostate cancer and baldness.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

The side gland of Suncus murinus is a good model for studying human sebaceous glands.

Gastric bypass surgery improved a woman's hormonal disorder without the need for medication.

Finasteride and dutasteride are effective in treating male hair loss but can cause sexual side effects and birth defects.

Using minoxidil with microneedling increases hair count for hair loss without serious side effects.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

The document's conclusion cannot be provided because the content is not accessible.

The combination of oral finasteride and dutasteride with topical minoxidil effectively promotes new hair growth in most people, with minimal side effects.

Dutasteride more effectively lowers DHT levels in men with enlarged prostates than finasteride.

DHT in the human prostate is produced through multiple pathways, not just from testosterone.

Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Muscles can make their own androgens, which may help muscle growth.

Testosterone affects hair follicles differently across body sites, with beard hair follicles showing more activity of a specific enzyme and presence of androgen receptors compared to scalp hair.

Flutamide combined with a low-dose birth control pill effectively reduces excessive hair growth in women with polycystic ovarian disease.

Testosterone can slow hair growth in adult monkeys, but a blocker called RU 58841 can counteract this and potentially help hair regrow.

Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.

Mutations in the NR3C1 gene cause a rare condition that affects hormone signaling and can lead to various symptoms, with dexamethasone as a treatment option.

5 alpha-reductase inhibitors like finasteride may lower prostate cancer risk and improve cancer screening.

Taking tadalafil and finasteride together is safe and effective for treating urinary symptoms and erectile dysfunction in men with enlarged prostates.

A reliable model for screening type II 5α-reductase inhibitors was created and validated.

Finasteride helps reduce prostate size and symptoms in BPH but is less effective than terazosin and works best for larger prostates.

The true incidence of post-Finasteride syndrome is unclear, and more research is needed.

The compounds tested could potentially treat hair loss and alopecia.

Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.

Both surgical and non-surgical hair loss treatments lack a standard treatment plan and sufficient patient satisfaction data.

Male pattern baldness is linked to higher levels of a certain receptor in the scalp, which leads to the shrinking of blood vessels and hair loss. Early treatment targeting this receptor could be more effective.

The document discusses male and female pattern hair loss, its diagnosis methods, FDA-approved treatments like finasteride and minoxidil, their side effects, and the role of lifestyle changes.

PRP is effective for treating hair loss, especially with other treatments.