Evaluation of the Efficacy and Safety of Topical and Oral Treatments on Hormonal and Androgenetic Alopecia

    January 2014 in “ Anales Médicos de la Asociación Médica del Centro Médico ABC ”
    Jeanet Espinosa Bautista, Juan Pablo Covarrubias, José Luis García
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    TLDR The combination of oral finasteride and dutasteride with topical minoxidil effectively promotes new hair growth in most people, with minimal side effects.
    In 2013, a nonrandomized, unblinded clinical trial was conducted to evaluate the efficacy and safety of a combination of oral finasteride and dutasteride with topical minoxidil in treating androgenetic alopecia over a period of 65 weeks. The study found that this combination promoted new hair growth. Only three out of 44 patients (6.8%) showed no significant changes, and only one reported sexual dysfunction problems. The effectiveness of the treatments was assessed by analyzing digitized images, providing quantitative data that allowed for comparison between different patient groups. No statistically significant differences were found between these groups.
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      community Coffee and androgenetic alopecia

      in Research/Science  12 upvotes 1 year ago
      The conversation discusses a claim that avoiding coffee can lead to significant hair regrowth in individuals with androgenetic alopecia. Participants are skeptical, with some sharing personal anecdotes that contradict the claim, and others discussing the potential role of caffeine in hair loss and the effectiveness of other treatments like finasteride and minoxidil.

      community A little over two years on Dut

      in Finasteride/Dutasteride  59 upvotes 2 months ago
      A 23-year-old male has been using Dutasteride for over two years to address hair thinning, with some success in temple regrowth but continued thinning on top. He is considering adding Minoxidil to his routine and is contemplating lifestyle changes like quitting smoking and drinking to improve hair density.

      community Why is everyone not directly advised Dutasteride?

      in Finasteride/Dutasteride  167 upvotes 2 months ago
      Dutasteride is less commonly prescribed for hair loss because it is not FDA-approved for this purpose, unlike finasteride, which is more accessible and preferred due to fewer side effects. Dutasteride may be more effective in reducing DHT but has a longer half-life and potentially more significant side effects.

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      in Research/Science  142 upvotes 10 months ago
      The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.

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