Evaluation of the Efficacy and Safety of Topical and Oral Treatments on Hormonal and Androgenetic Alopecia

    Jeanet Espinosa Bautista, Juan Pablo Covarrubias, José Luis García
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    TLDR The combination of oral finasteride and dutasteride with topical minoxidil effectively promotes new hair growth in most people, with minimal side effects.
    In 2013, a nonrandomized, unblinded clinical trial was conducted to evaluate the efficacy and safety of a combination of oral finasteride and dutasteride with topical minoxidil in treating androgenetic alopecia over a period of 65 weeks. The study found that this combination promoted new hair growth. Only three out of 44 patients (6.8%) showed no significant changes, and only one reported sexual dysfunction problems. The effectiveness of the treatments was assessed by analyzing digitized images, providing quantitative data that allowed for comparison between different patient groups. No statistically significant differences were found between these groups.
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