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    GlossaryHormonal Hair Loss (Hormonal Alopecia)

    hormone imbalances cause hair thinning or shedding

    Hormonal Hair Loss, also known as Hormonal Alopecia, refers to hair loss caused by imbalances or changes in hormone levels. Common examples include androgenetic alopecia, where dihydrotestosterone (DHT) affects hair follicles, and hair loss related to thyroid disorders, pregnancy, menopause, or polycystic ovary syndrome (PCOS). This type of hair loss can affect both men and women and often requires medical evaluation to identify and treat the underlying hormonal issue.

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      learn Finasteride

      Frontline, gold standard treatment for combatting androgenic alopecia
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      learn HMI-115

      much-hyped research compound targeting prolactin receptor in scalp

      learn Stemoxydine

      chemical from L'Oreal that encourages hair to enter growth phase

      learn Alfatradiol

      a synthetic estrogen used topically as an anti-androgen

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      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  828 upvotes 5 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.
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      community any news about DUPA (Diffuse unpatterned alopecia)?

      in Research/Science  8 upvotes 2 years ago
      The conversation discusses diffuse unpatterned alopecia (DUPA) and its possible causes, including sensitivity to DHT, not being androgenic alopecia, being diffuse alopecia areata, or hormonal issues. Treatments mentioned include topical melatonin, Clobetasol Propionate for alopecia areata, and the lack of results from using finasteride, dutasteride, and minoxidil.

      community Nizoral doesn't seem to be working. Rogaine not suggested by doctor due to cost and poor track record on females. Ideas?

      in Ketoconazole  24 upvotes 6 years ago
      A woman experiencing hair loss and facial hair growth suspects PCOS or androgenic alopecia and is considering treatments like Rogaine, but is concerned about the cost. She has tried various hair care methods and is awaiting a hormone doctor appointment, while others suggest she may have a hormonal imbalance and recommend seeing a gynecologist or trying cheaper versions of Rogaine.

      community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

      in Research/Science  62 upvotes 1 year ago
      Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.