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research Evaluation of the efficacy and safety of topical and oral treatments on hormonal and androgenetic alopecia

January 2014 in “Anales Médicos de la Asociación Médica del Centro Médico ABC”

This study suggests that a combination of topical minoxidil with oral finasteride or dutasteride promotes hair growth in treating androgenetic alopecia, with only minor safety concerns reported.

research Androgenetic alopecia: evaluation of hormonal profile and its systemic implications

December 2023 in “International Journal of Research in Dermatology”

This study evaluated hormonal differences in males with early androgenetic alopecia, finding increased serum testosterone, prolactin, LH, LH/FSH, and FAI levels, with decreased FSH and SHBG levels, compared to controls without hair loss.

Permanent Alopecia in Patients with Breast Cancer After Taxane Chemotherapy and Adjuvant Hormonal Therapy: Clinicopathologic Findings in a Cohort of 10 Patients

research Permanent alopecia in patients with breast cancer after taxane chemotherapy and adjuvant hormonal therapy: Clinicopathologic findings in a cohort of 10 patients

31 citations , March 2017 in “Journal of The American Academy of Dermatology”

This study observed various patterns of permanent alopecia in breast cancer patients treated with taxanes and adjuvant hormonal chemotherapy, hypothesizing disruptions in hair follicle cycles due to chemoinflammatory and hormonal factors.

research Pattern Alopecia during Hormonal Anticancer Therapy in Patients with Breast Cancer

9 citations , January 2014 in “Annals of Dermatology”

In this report, five female patients undergoing hormonal anticancer therapy for breast cancer prevention developed pattern alopecia, which the authors attribute to androgen-estrogen imbalance caused by antiestrogenic drugs.

research BIOCHEMICAL AND HORMONAL FACTORS IN THE DEVELOPMENT OF ALOPECIA IN WOMEN: DIAGNOSTIC SIGNIFICANCE FOR TRICHOLOGICAL PRACTICE

April 2026 in “Academia Polonica.”

In this study, researchers explored the hormonal and biochemical factors linked to alopecia in women, highlighting how various factors such as nutrient deficiencies, hormonal imbalances, and stress may influence hair loss patterns, necessitating a comprehensive diagnostic and treatment approach in trichological practice.

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Community Join

5 / 733 results

community ICYMI: Eirion ET-02’s Successful Phase 1 Trial Results for Androgenic Alopecia Treatment

46 upvotes 1 year ago

ET-02 showed significant hair growth in five weeks, outperforming minoxidil, with a non-hormonal mechanism that avoids side effects of treatments like finasteride. A phase 2 trial is planned to further assess ET-02's efficacy and safety.

community Minoxidil is a 5ar inhibitor according to research

150 upvotes 11 months ago

Minoxidil may inhibit androgen receptors and affect hormonal pathways, potentially explaining its effectiveness in treating androgenetic alopecia (AGA). Users discuss its varying effectiveness on scalp versus facial hair and note fewer side effects with topical use compared to oral.

community Female diffuse hair loss on spiro with irregular periods (photos) + genetic hair loss

in Female 16 upvotes 1 year ago

A 34-year-old woman is experiencing diffuse hair loss and irregular periods, possibly due to long-term spironolactone use. She is considering minoxidil and finasteride for treatment and seeking medical advice for androgenic alopecia and hormonal imbalances.

community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

63 upvotes 2 years ago

Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

community Hair Loss Factors in Moms: Analyzing Hormonal Changes, Stress, Genetics, and More

4 upvotes 3 years ago

Hair loss in moms can be caused by hormonal changes, stress, genetics, and nutritional deficiencies. Solutions include hair toppers, Minoxidil, PRP therapy, and a healthy diet with supplements.

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Learn

10 / 801 results

learn Scalp Micropigmentation

Is scalp micropigmentation suitable for all types of hair loss? Scalp micropigmentation is generally suitable for various types of hair loss.

learn Hair Transplant

Can women get hair transplants? Women can get hair transplants, and procedures are tailored to their specific hair loss patterns.

learn Follistatin

How does follistatin compare to finasteride or dutasteride for treating androgenic alopecia? Finasteride and dutasteride are prescription drugs with large controlled trials showing they lower DHT and slow androgenic hair loss, at the cost of documented hormonal side effects; follistatin targets a different, regenerative pathway but has only one small phase 1 human trial behind it, so it is experimental with unknown safety rather than a comparable alternative.

learn Finasteride

Frontline, gold standard treatment for combatting androgenic alopecia

learn Overview

learn HMI-115

much-hyped research compound targeting prolactin receptor in scalp

learn Stemoxydine

chemical from L'Oreal that encourages hair to enter growth phase

learn Alfatradiol

a synthetic estrogen used topically as an anti-androgen

learn Lavender

Is lavender effective for hormonal hair loss or just stress? Lavender may help with stress-related hair loss but has limited evidence for hormonal hair loss.

learn procapil

Want to stop hormonal hair loss without touching your hormone levels? Procapil could block the enzyme doing the damage. Procapil's supplier describes it as inhibiting 5-alpha reductase at the scalp without changing hormone levels, but the published support is cell and animal work plus one small human study of a caffeine-plus-Procapil formula. It is a cosmetic ingredient, not an approved hair-loss treatment, and no trial has compared it with finasteride or minoxidil.

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Clinics

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