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Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

MicroRNAs play a crucial role in skin and hair health, affecting everything from growth to aging, and could potentially be used in treating skin diseases.

Blocking JAK/STAT pathways can help treat hair loss from alopecia areata.

CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.

Understanding how EDC genes are regulated can help develop better drugs for skin diseases.

Hair microRNAs could be effective biomarkers for diagnosing scleroderma.

Cysteine-rich keratins evolved independently in mammals, reptiles, and birds for hard skin structures like hair, claws, and feathers.

The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.

Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.

Cell-based therapies using dermal papilla cells and adipocyte lineage cells show potential for hair regeneration.

Sex hormone treatments can increase muscle mass in older adults but have inconsistent effects on muscle function and may carry cardiovascular risks.

Melatonin helps Cashmere goats grow more hair by affecting certain genes and cell pathways.

Cellular senescence has both cancer-blocking and cancer-promoting effects, and targeting senescent cells may improve health and lifespan.

Vitamin D3 can help improve hair growth by enhancing the function of specific skin cells and could be useful in hair regeneration treatments.

Skin organoids are a promising new model for studying human skin development and testing treatments.

The research concluded that selection significantly shaped the genetic variation of the X chromosome, with certain regions affected by past selective events.

The Ovol2-Zeb1 circuit is crucial for skin healing and hair growth by guiding cell movement and growth.

Hair follicles are valuable for regenerative medicine and wound healing.

New treatments targeting immune pathways show promise for severe hair loss but need more research for safety and effectiveness.

Immune cells help regulate hair growth, and better understanding this can improve hair loss treatments.

Hair can regrow in large wounds through a process similar to how hair forms in embryos, and understanding this could lead to new treatments for hair loss or scarring.

Researchers found genes that control hair color and growth change before the visible coat color changes in snowshoe hares.

Ancient Chinese goats evolved cashmere-producing traits due to selective breeding, particularly in genes affecting hair growth.

iNKT cells can help prevent and treat alopecia areata by promoting hair regrowth.

Female donor to male recipient sex mismatch and positive ACA-IgG are key risk factors for vitiligo and alopecia areata in chronic GvHD patients.

Regenerative therapies show promise for treating vitiligo and alopecia areata.

lncRNA XLOC_008679 and gene KRT35 affect cashmere fineness in goats.

DNA methylation and long non-coding RNAs are key in controlling hair growth in Cashmere goats.

Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.

Men with hair loss have more DNA changes in back-of-head hair follicles, possibly protecting them from thinning.