25 citations,
May 1994 in “Journal of Investigative Dermatology” Researchers found a new gene, hacl-1, that is active in mouse hair follicles during hair growth and may be important for hair biology.
23 citations,
January 2020 in “Frontiers in Pharmacology” Dihydrotestosterone affects hair growth by changing the Wnt/β-catenin pathway, with low levels helping and high levels hindering growth.
23 citations,
May 2016 in “American Journal of Pathology” The research suggests that a specific skin gene can be controlled by signals within and between cells and is wrongly activated in certain skin diseases.
21 citations,
August 1994 in “Clinical endocrinology” 5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.
17 citations,
May 2019 in “Diabetes and Metabolic Syndrome: Clinical Research and Reviews” High fasting insulin levels in women with PCOS are linked to a higher risk of heart and metabolic problems.
11 citations,
April 2019 in “International Journal of Molecular Sciences” Certain genetic variations in OCT1 may improve insulin sensitivity with metformin in women with PCOS.
11 citations,
March 2017 in “Journal of Biomedical Semantics” The Drug Ontology was updated to better classify drugs for hypertension, malaria, and opioid abuse, and to allow for more accurate research queries.
11 citations,
January 2000 in “The Journal of Steroid Biochemistry and Molecular Biology” LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.
10 citations,
November 2017 in “Journal of Investigative Dermatology” A mutation in the FAM83G gene is linked to skin and hair abnormalities in two related individuals.
10 citations,
July 2011 in “Springer eBooks” Carboxytherapy can improve skin conditions with few side effects, but results may vary and are not guaranteed.
9 citations,
September 2016 in “Medical Clinics of North America” Eating less and exercising more, with personalized diet plans and realistic goals, can lead to weight loss and better health, but more research is needed for long-term success.
6 citations,
November 2020 in “Molecular and Cellular Endocrinology” Androgens reduce BMP2, which weakens the ability of certain cells to help hair stem cells become different types of cells.
5 citations,
April 2019 in “Phytochemical Analysis” The new ELISA method is reliable and eco-friendly for checking the quality of Pueraria candollei.
4 citations,
September 2020 in “Annals of Translational Medicine” Concentrated nanofat helps mice grow hair by activating skin cells and may be used to treat hair loss.
1 citations,
March 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” The hair treatment made hair grow faster and thicker and strengthened the hair roots.
1 citations,
October 1996 in “Journal of Cutaneous Medicine and Surgery” Gene therapy shows promise for treating skin disorders and cancer, but faces technical challenges.
October 2023 in “Frontiers in endocrinology” Effective PCOS treatments require targeting specific signaling pathways.
January 2019 in “Springer Reference Medizin” Follicle Stimulating Hormone is important for fertility.
Tissue from dog stem cells helped grow hair in mice.
The hydrogel with 20% Hibiscus rosa-sinensis extract was the best for potential therapeutic use.
117 citations,
May 2017 in “Human Reproduction Update” The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.
57 citations,
March 2019 in “Immunity” The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.
The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.
60 citations,
July 2014 in “Autophagy” The protein FLCN is involved in cellular cleanup and is regulated by ULK1.
115 citations,
August 2008 in “The Journal of Clinical Endocrinology & Metabolism” Thyroid hormones help hair grow, reduce hair loss, and increase hair pigment.
19 citations,
July 2020 in “EBioMedicine” A gene variant increases the risk of a type of hair loss by affecting hair protein production.
6 citations,
May 2020 in “Scientific reports” Researchers identified genes and proteins that may influence wool thickness in sheep.
78 citations,
November 2005 in “Endocrinology” Hairless protein can block vitamin D activation in skin cells.
32 citations,
December 2019 in “The Journal of clinical investigation/The journal of clinical investigation” A protein called IL-36γ causes skin side effects from certain cancer treatments when combined with a common skin bacteria.
25 citations,
July 2016 in “Molecular biology of the cell” A protein in plants needs to bind two lipids to help with root hair growth, and this process is similar across different plant species.