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Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

Androgens can both increase and decrease hair growth in different parts of the body.

Lactate production is important for activating hair growth stem cells.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

The peptide GHK-Cu helps heal and remodel tissue, improves skin and hair health, and has potential for treating age-related inflammatory diseases.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Estrogen therapy can reduce skin aging but has cancer risks.

Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Macrophages help heal nerves by aiding the maturation of Schwann cells and are important for nerve repair.

Early detection and intensive treatment of diseases caused by Staphylococcus aureus toxins are crucial for reducing severe health effects.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.

Tiny particles from stem cells help activate hair growth cells and encourage hair growth in mice without being toxic.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.

A mother's PPARγ is crucial for preventing harmful milk that can cause inflammation and growth problems in babies.