research Formulation, Evaluation, and Stability Studies of Dutasteride-Loaded Niosomal Gel
The gel effectively delivers dutasteride for hair loss treatment and remains stable for 90 days.
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research Resistance Training Improves Finasteride-Induced Protein Homeostasis Disruption in Rat Skeletal Muscle
Resistance exercise helps improve muscle protein balance disrupted by finasteride.
research Impact of Dutasteride on Spermatogenesis and Oxidative Stress in Rats
Dutasteride does not seem to change rat spermatogenesis or oxidative stress.
research The Role of Fractional Laser-Assisted Drug Delivery in Enhancing the Efficacy of Topical Bimatoprost Solution in the Treatment of Alopecia Areata: An Intra-Patient Comparative Randomized Clinical Trial
Using a laser with bimatoprost solution works better for hair regrowth in alopecia areata than bimatoprost alone.
research QSAR Analysis of a Series of Hydantoin-Based Androgen Receptor Modulators and Corresponding Binding Affinities
Researchers developed reliable models to predict how well certain compounds bind to androgen receptors, emphasizing the importance of atomic electronegativity.
research Finasteride-Associated Male Infertility
Finasteride may worsen infertility in men with existing issues, but stopping it can improve sperm health.
research 5α-Reductase Inhibitors in the Treatment of Androgenetic Alopecia
Finasteride improves hair growth in men with androgenetic alopecia.
research Separation of Finasteride and Analogues
Finasteride and analogues separated using LC-MS-MS technique.
research Post-Finasteride Syndrome: An Induced Delusional Disorder with the Potential of a Mass Psychogenic Illness?
PFS might be a delusional disorder with potential to become mass psychogenic illness.
research The Effect of 5-Alpha Reductase Inhibitor on Male Reproductive Function
5-α reductase inhibitors do not significantly affect male reproductive function but may reduce semen volume.
research Treatment of Benign Essential Blepharospasm With Finasteride
Finasteride helps treat eyelid spasms.
research Editorial Comment
research Activated Polyamine Catabolism Depletes Acetyl-CoA Pools and Suppresses Prostate Tumor Growth in TRAMP Mice
Overexpressing SSAT enzyme reduces prostate tumor growth in mice.
research Heart Failure Due to Cardiac Transthyretin Amyloidosis
A 90-year-old man was diagnosed with heart failure due to wild-type transthyretin cardiac amyloidosis.
research Finasteride: Suicidality or Psychological Adverse Events
Finasteride use linked to increased suicidality in patients under 45.
research This Month in Adult Urology
The document highlights recent findings and treatments in urology, including prostate cancer diagnostics, urinary incontinence, and new therapies.
research Oral Bicalutamide for Female Pattern Hair Loss: A Pilot Study
Bicalutamide improves hair density in women safely.
research High-Throughput and Direct Measurement of Androgen Levels Using Turbulent Flow Chromatography Liquid Chromatography-Triple Quadrupole Mass Spectrometry to Discover Chemicals That Modulate Dihydrotestosterone Production in Human Prostate Cancer Cells
Researchers found four natural compounds that can change DHT levels in prostate cancer cells.
research Symptoms of Hypogonadism Caused by 5α-Reductase Inhibitors
A man's low testosterone and related symptoms improved after he stopped taking hair loss drugs.
research Flagellate Shiitake Mushroom Reaction With Histologic Features of Acute Generalized Exanthematous Pustulosis
Eating shiitake mushrooms caused a man to develop a rash similar to a skin condition known as AGEP.
research Finasteride: The First 5 Alpha-Reductase Inhibitor
research Finasteride Blocks Progesterone Synthesis in MA-10 Leydig Tumor Cells
Finasteride blocks progesterone production in specific tumor cells, potentially causing side effects.
research Production of Biologically Active Oxidized Derivatives of Finasteride Through Metabolism by Aspergillus Niger Culture
Aspergillus niger culture creates two finasteride derivatives with enzyme-inhibiting effects.
research Improvement of General Symptoms in a Chronic Psychotic Patient Treated with Finasteride: Case Report
Finasteride improved symptoms in a schizophrenia patient.
research Voltammetric Reduction of Finasteride at Mercury Electrode and Its Determination in Tablets
New, cheaper method measures finasteride in tablets accurately and quickly.
research News in Brief: Taiwanese Study on Dicentrine, Japanese Study on T-588, Provir's Effects on Herpes, and LY191704 as a 5α-Reductase Inhibitor
Dicentrine reduced heart disease risk factors in rats, T-588 protected mice brains without side effects, Provir blocked herpes virus and lessened mouse symptoms, and LY191704 could treat hair loss and prostate issues.
research Comparison of Finasteride, a 5α Reductase Inhibitor, and Various Commercial Plant Extracts in In Vitro and In Vivo 5α Reductase Inhibition
Finasteride effectively inhibits 5α reductase, while plant extracts like Permixon and Bazoton don't show significant results.
research Azasteroids as Inhibitors of Testosterone 5α-Reductase in Mammalian Skin
Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.
research Prolonged Treatment with Finasteride (a 5α-Reductase Inhibitor) Does Not Affect Bone Density and Metabolism
Long-term finasteride use doesn't change bone density or metabolism.
research The 5α-Reductase Inhibitor Finasteride Is Not Associated With Alterations in Sleep Spindles in Men Referred for Polysomnography
Finasteride doesn't affect sleep spindles in men.