Finasteride: Suicidality or Psychological Adverse Events

    November 2020 in “ Reactions Weekly ”
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    TLDR Finasteride use linked to increased suicidality in patients under 45.
    A study published in JAMA Dermatology found a significant association between finasteride use for androgenetic alopecia and suicidality in patients under 45 years old. The study evaluated adverse events reported to WHO's Vigibase and found 356 reports of suicidality and 2926 reports of depression or anxiety in primarily male patients. The authors note that the disproportional signals "could result from adverse effects, such as persistent sexual dysfunction, having a greater toll on younger patients using finasteride to treat a nonurologic condition". Health care professionals are advised to conduct a full evaluation and a detailed, personalized risk-benefit assessment for patients before prescribing finasteride.
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      community EU Shouldn't Ban Fin & Dut: PFS is NOT REAL.

      in Research/Science  11 upvotes 5 months ago
      Finasteride and Dutasteride do not cause depression or "Post Finasteride Syndrome," with concerns often linked to the nocebo effect and preexisting mental health issues. The EU is unlikely to ban these drugs, but access may become more restricted due to ongoing debates.

      community Massive study on finasteride side effects released

      in Finasteride/Dutasteride  83 upvotes 2 years ago
      The release of a study on 5a-reductase inhibitors (finasteride and dutasteride) which showed an increased risk of depression, dementia, decreased libido, and reduced semen load as potential side effects; discussion around other forms of hair loss treatments such as topical minoxidil, RU58841, or opting to accept baldness; and advice to consider professional help for deeper issues related to hair loss.

      community M20 Vitamin D Deficiency and Hair Thinning

      in General  75 upvotes 3 weeks ago
      A 20-year-old is experiencing hair thinning due to vitamin D deficiency and has completed a vitamin D prescription without seeing improvement. Suggestions include waiting a few months for potential regrowth or considering treatments like minoxidil or finasteride for androgenetic alopecia.

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