Heart Failure Due to Cardiac Transthyretin Amyloidosis

A 90-year-old male patient presented with symptoms of decompensated heart failure, including dyspnea, orthopnea, and lower limb edema. Diagnostic tests, including electrocardiogram, echocardiogram, and magnetic resonance imaging, indicated cardiac amyloidosis. Further testing confirmed transthyretin cardiac amyloidosis without gene mutations, characterizing it as wild-type. The patient had a history of glaucoma, benign prostatic hyperplasia, and depression, and was on multiple medications. Physical examination showed he was in a regular general state with stable vital signs, except for an elevated heart rate.