Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study formulated nanostructured lipid carriers with curcumin, using specific surfactants, to enhance its stability and bioavailability for more effective androgenetic alopecia treatment.

This study found that sulforaphane-rich broccoli sprout extract significantly accelerated hair regrowth in a mouse model of androgenetic alopecia, suggesting its potential as a safe and effective natural therapy.

This study developed a peptide-based topical delivery system that enhanced hair growth with reduced systemic exposure to finasteride, showing efficacy comparable to 5% minoxidil in vivo while using significantly less finasteride than oral doses.

This study found that soy-based nanofibrous scaffolds enhanced wound closure and tissue regeneration via the ER-β pathways in both mouse and human skin, suggesting a potential for effective wound healing applications.

In this study, 15d-PGJ2 administered in a topical cream inhibited oxidative and inflammatory skin changes caused by UVB radiation in hairless mice, suggesting it as a promising treatment approach.

This study identified several compounds from traditional Chinese medicines that may inhibit prostaglandin D2 synthase, potentially providing promising candidates for treating androgenic alopecia with minimal adverse skin reactions.

This study introduced a novel nonsteroidal androgen receptor antagonist that effectively controls sebum production in the golden Syrian hamster ear model through targeted follicular delivery.

This study found that clove oil and LPGSE pretreatment increased finasteride skin permeability, while extending urea pretreatment reduced its penetration.

This abstract mentions that while synthetic drugs like minoxidil and finasteride for androgenic alopecia have side effects, the characteristics of popular natural alternatives, such as soybean, remain largely unreported, despite consumer preference for these products.

This study found that phytosterols extracted from moringa seed oil may act as potential anti-alopecia agents by inhibiting the 5α-reductase enzyme, with ergostadienol showing particularly high affinity and stability in in silico simulations.

This laboratory study found that PI extract, along with its metabolites Ang and Mac, inhibited cell proliferation and protein expression linked to pathways involved in BPH, suggesting potential for therapeutic use, although the Ang-Mac combination showed no significant effect on apoptosis through the p53 pathway.

This study found that Asparagus racemosus root extract significantly reduced facial sebum production and pore size in male volunteers, suggesting potential application as an anti-sebum ingredient in cosmetics.

This study found that latanoprost induces significant growth and pigmentation of lashes and ancillary hairs, with effects mirroring both brief and chronic treatments observed in patients and animal models.

In this study, OEA was found to significantly enhance sebaceous lipogenesis and potentially reduce inflammation in human sebocytes, suggesting it as a promising candidate for treating skin dryness.

This study found that high-dose pterostilbene potentially reduced prostate hyperplasia and had strong antioxidant effects in male rats with benign prostatic hyperplasia, suggesting it might be more effective than vitamin C and resveratrol in similar contexts.

This study found that Gynostemma pentaphyllum leaf hydrodistillate (GPHD) promoted hair growth in mice similarly to minoxidil and upregulated growth factor expression via the AKT/β-catenin signaling pathway, with damulin B identified as an active component contributing to these effects.

This study found that the compound androstane-17-carboxamide 6 may serve as a lead for new drugs to treat BPH and prostate cancer by reducing the weight of androgen-dependent glands.

In this study, researchers observed that using an Avena strigosa seed extract on chemically damaged hair significantly improved hair properties, including strength, gloss, and surface quality, by reinforcing keratin bonding and sealing cuticle damage.

Propolis extract can promote hair growth and increase keratin production.

This study reported that peanut callus extract, rich in resveratrol, significantly stimulated hair growth and reduced hair loss in an in vitro model and a clinical trial, showing promise as a cosmetic bioactive ingredient.

This case report discusses the use of a prostaglandin analogue for treating eyebrow loss in a patient with frontal fibrosing alopecia, but provides no new clinical results.

This study found that certain metabolites from the plants Bidens pilosa, Calophyllum inophyllum, and Fagraea berteroana may support hair follicle growth by promoting dermal papilla cell proliferation, supporting their traditional use in hair care.

This study observed that topical prostaglandin treatments may protect against hair follicle injury during chemotherapy, as indicated by preserved eyelashes in patients using these treatments.

This study investigated the potential of nutmeg-derived phytochemicals as anti-alopecia agents using molecular docking and simulations, finding that geranylgeraniol exhibited significant binding stability and potential efficacy against androgenetic alopecia comparable to finasteride and superior to minoxidil.

This study identified a new compound from fermented Carica papaya L. with moderate antioxidant and potent hair growth-stimulating activities in vitro.

In this study, latanoprost was found to stimulate VEGF protein synthesis in human dermal papilla cells, suggesting it may contribute to promoting hair growth.

This study found that a specific amino-pyridine compound showed potent androgen receptor antagonist activity, stimulating hair growth in mice and reducing sebum production in a hamster model.

This study found that transdermal delivery of finasteride using biomimetic Platycladi cacumen-derived nanovesicles enhanced hair regrowth in a mouse model of androgenetic alopecia, outperforming minoxidil by improving skin permeation, reducing oxidative stress, and boosting local drug retention.

This study found that bimatoprost stimulated hair growth in both human scalp follicle cultures and mouse pelage in vivo, suggesting it might offer a promising treatment for scalp alopecias.