Effects of Latanoprost on Vascular Endothelial Growth Factor Protein Synthesis in Human Dermal Papilla Cells

    January 2006
    Fan Wu
    TLDR Latanoprost increases VEGF protein in human cells, which may help hair growth.
    In the 2006 study, researchers investigated the effects of latanoprost on vascular endothelial growth factor (VEGF) protein synthesis in human dermal papilla cells (DPCs). They treated DPCs with five different concentrations of latanoprost for 72 hours and measured VEGF protein levels using ELISA kits. The results showed that VEGF protein synthesis was significantly increased in the DPCs treated with latanoprost at all concentrations except for the lowest one at 0.16 ng/mL. The increase in VEGF protein synthesis was dose-dependent. The study concluded that latanoprost stimulates VEGF protein synthesis in human DPCs, suggesting a potential role in promoting hair growth.
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