18 citations
,
July 2016 in “Clinics in dermatology” This article discusses the interplay of skin, immunity, and nutrition, highlighting dietary and probiotic options for managing skin conditions, but reports no new clinical findings.
2 citations
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July 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that oral administration of Thauera sp. strain GDN1 reduced serum androgen levels in male mice by about 50%, suggesting its potential as a probiotic treatment for hyperandrogenism.
January 2026 in “Microorganisms” In a DNFB-induced mouse model of atopic dermatitis, this study found that both topical and oral formulations of the probiotic Bifidobacterium animalis J12 improved AD symptoms through distinct mechanisms, with topical applications reducing local inflammation and oral administration enhancing gut microbiota and reducing systemic inflammation.
October 2025 in “International Journal of Nutrology” This systematic review found that exosomes and gut microbiota play a significant role in skin regenerative processes, suggesting that gut health is crucial for maintaining aesthetically healthy skin, and probiotic treatments may support traditional dermatological therapies for inflammatory skin diseases.
April 2024 in “Frontiers in microbiology” This study found that certain gut microbiota are linked with androgenetic alopecia, identifying both risk and protective microbial factors, which could inform targeted probiotic strategies for managing AGA.
This paper highlights the role of the skin microbiome in influencing skin and hair conditions, suggesting that understanding these microbial communities could aid in developing new probiotic or antibiotic treatments for disorders like alopecia and skin diseases.
143 citations
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May 2022 in “Pharmaceuticals” This review discusses alginate-based delivery systems for probiotics, highlighting recent advances, challenges, and future directions, but reports no new clinical findings.
14 citations
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September 2023 in “Frontiers in Nutrition” This source observed that while supplementation with pro-, pre-, and synbiotics showed some beneficial effects for PCOS-related outcomes, the evidence quality was deemed low to very low, highlighting the need for further well-designed randomized controlled trials in women with PCOS.
9 citations
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July 2021 in “Journal of Medicinal Food” This study found that consuming Lactobacillus paracasei HY7015 promoted hair growth and follicle maturation in mice, likely through stimulating dermal papilla cell proliferation and growth factor secretion.
1 citations
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January 2015 in “MOspace Institutional Repository (University of Missouri)” This study found that applying 120L ha-1 yr-1 of SCD Probiotics to soil significantly increased soil microbial biomass and enzyme activity compared to lower doses and control, but showed no impact on auxin production.
September 2022 in “Research Square (Research Square)” This study found that while pro-, pre-, and synbiotics may have beneficial effects on certain PCOS-related outcomes, the certainty of this evidence is low to very low.
35 citations
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August 2021 in “BMC Medical Genomics” This study found that serum metabolic profiles differ significantly between polycystic ovary syndrome patients and healthy controls, highlighting potential metabolic markers for diagnosing and prognosing PCOS.
9 citations
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April 2024 in “Heliyon” This review highlighted significant properties of probiotics that can promote hair growth and reduce dandruff, offering guidance for future research to scale these findings to pilot studies.
85 citations
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August 2021 in “Materials & Design” This review summarizes advancements in biomaterial-based encapsulation of probiotics for diverse biomedical uses and reports no new clinical results, while outlining current challenges and future research directions.
8 citations
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January 2021 in “Fermentation” This article discusses the potential role of probiotics and synbiotics in managing hirsutism through insulin resistance but reports no new clinical results, calling for further research.
4 citations
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March 2022 in “BioEssays” This paper reviews how studying the microbiome of the freshwater polyp Hydra can inform new, microbiome-targeting therapies for human hair follicle and skin diseases; it presents no new experimental findings.
2 citations
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November 2022 in “Bioscience Reports” This review explores the similarities between polycystic ovary syndrome and hemochromatosis in terms of iron overload and suggests that addressing gut dysbiosis might help manage iron levels in these conditions.
January 2024 in “Wiadomości Lekarskie” This study found that using Lactobacillus reuteri DSM 17938 probiotics significantly improved IBS symptoms in children, with optimal therapy duration suggested to be 1-3 months based on symptom and calprotectin level reductions.
June 2015 in “Journal of the turkish academy of dermatology” This review revisits the principles regarding the critical role of diet and nutrition in managing certain skin diseases but reports no new findings.
January 2013 in “Hunan Agricultural Sciences” In this study, Lactobacillus reuteri and Bacillus natto were found to potentially replace Aureomycin in alleviating weaning stress in piglets, based on growth, diarrhea rate, immunity, and other health indicators.
December 2022 in “Türk biyokimya dergisi” The conclusions are: fecal short-chain fatty acids may help prevent cancer, fiber intake can reduce obesity, weight loss is hard for obese people, low BMI cancer patients are more prone to chemotherapy side effects, intermittent fasting benefits gut health, cherry laurel has health benefits in rats, certain gene variations can increase stress in hair loss patients, fecal acids can affect blood sugar levels, cold agglutinin can affect blood test results in autoimmune patients, and people with Crohn's disease have higher levels of a certain chemical in their blood.
13 citations
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January 2005 in “Chemical and Pharmaceutical Bulletin” This study reported that newly synthesized progesterone derivatives significantly reduced prostate weight in testosterone-treated hamsters, with 5alpha-reductase inhibitory activity dependent on the size of the substituent at C-17.
8 citations
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July 2018 in “Analytical sciences” This study reported that derivatization with 5-butylpicolinic acid improved the sensitivity for detecting testosterone and DHT in saliva using LC-ESI-MS/MS, with minimal interference from the saliva matrix.
15 citations
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December 2020 in “The Journal of General Physiology” This study found that acid regulation of the TRPV3 channel can inhibit its function from outside the cell while facilitating it from inside, providing insights into skin barrier and disorder mechanisms related to tissue acidosis.
18 citations
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December 2005 in “Journal of Medicinal Chemistry” In this study, novel substituted benzoyl benzoic acids and phenylacetic acids were potent and selective inhibitors of human steroid 5alpha-reductase type 2, with one compound showing promising bioavailability in rats for potential clinical evaluation.
28 citations
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January 2016 in “RSC Advances” This study found that non-toxic polycarboxylic acids can achieve satisfactory hair perming effects with limited strength loss, suggesting they have potential as a safer alternative to harmful perming chemicals.
19 citations
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June 1999 in “Steroids” This study found that compound 10 inhibited testosterone conversion to DHT in hamster flank organs and seminal vesicles, whereas compound 11's inhibitory effect varied with dose, linked to halogen electronegativity differences.
4 citations
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December 2024 in “European Journal of Medicinal Chemistry” This study reported the development of new pyrazole-based MPC inhibitors that effectively inhibit mitochondrial pyruvate transport, showing potential as therapeutic candidates for conditions like metabolic dysfunction-associated steatohepatitis without activating PPARγ.
15 citations
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April 2008 in “Steroids” This study found that pregnane derivatives with higher lipophilicity, like compound 9d, had stronger androgen receptor binding and greater antiandrogenic effects in rats, correlating relative binding affinity with log P values.
13 citations
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May 2011 in “Bioorganic & Medicinal Chemistry” This study identified certain benzopyran derivatives with a bulky tert-butyloxycarbonylamino group as effective KATP channel openers that inhibit insulin secretion in rat pancreatic islets.