Major Clinical Outcomes Of The Gut Microbiota-Skin Axis Through Exosomes And Probiotics: A Systematic Review

    October 2025 in “ International Journal of Nutrology ”
    Armando Zúñiga, Elisa Grández Mesías, Andréia Borges Scriboni
    The systematic review analyzed 23 studies to explore the relationship between gut microbiota and skin health, focusing on the role of probiotics and exosomes. The findings suggest that exosomes and gut microbiota significantly influence skin regenerative processes, highlighting their potential in developing personalized skin health strategies. Despite some studies having a high risk of bias, the overall results were consistent, indicating that manipulating the gut microbiota is crucial for achieving aesthetically healthy skin. Treatments that enhance gut health are essential as adjunctive therapy for inflammatory skin diseases and may improve the effectiveness of standard dermatotherapy.
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