2 citations,
February 2018 in “InTech eBooks” TNF-alpha inhibitors can cause various immune-related skin issues.
September 2024 in “The Italian Journal of Pediatrics/Italian journal of pediatrics” This case report and literature review discuss a 6-year-old girl who developed severe multisystem inflammatory syndrome in children (MIS-C) 30 days after receiving her second dose of the COVID-19 vaccine, despite no prior detected SARS-CoV-2 infection. She presented with fever, abdominal pain, rash, and other symptoms, and was diagnosed with MIS-C through positive anti-SARS-CoV-2 antibodies. Treatment with intravenous immunoglobulins and methylprednisone led to initial improvement, but she later developed pancreatitis and severe neurological symptoms, which resolved after 2 months. She also experienced transient hair loss (telogen effluvium) 3 months post-symptom onset. After 12 months, she showed no symptomatic sequelae. The case suggests a potential link between COVID-19 vaccination and MIS-C in young children and underscores the importance of prompt diagnosis and treatment.
19 citations,
September 2019 in “EMBO molecular medicine” Blocking TSLP reduces skin inflammation and cell overgrowth in psoriasis.
January 2014 in “Springer eBooks” Inflammasome proteins can indicate the severity and treatment response of various diseases and injuries.
32 citations,
March 2014 in “PLOS ONE” Mice lacking fibromodulin have disrupted healing patterns, leading to abnormal skin repair and scarring.
26 citations,
March 2014 in “International journal of pharmaceutics” Researchers created a skin treatment that could effectively deliver medication into hair follicles.
2 citations,
May 2023 in “Life” Plumbagin may help protect cells, reduce inflammation, and has potential for treating various diseases, but more research is needed.
127 citations,
January 2013 in “PLOS ONE” Probiotic bacteria improved skin and hair health in aged mice.
43 citations,
August 2016 in “International Journal of Nanomedicine” Eupafolin nanoparticles help protect skin cells from damage caused by air pollution.
42 citations,
April 2021 in “Journal of clinical pharmacology” Baricitinib helps treat several diseases, including COVID-19, but has side effects and needs careful monitoring.
28 citations,
October 2019 in “Seminars in Cell & Developmental Biology” Hair can regrow in large wounds through a process similar to how hair forms in embryos, and understanding this could lead to new treatments for hair loss or scarring.
28 citations,
September 2013 in “Expert Opinion on Therapeutic Patents” New resveratrol-related compounds show promise for treating various health issues but need more research for clinical use.
16 citations,
September 2020 in “British journal of dermatology/British journal of dermatology, Supplement” The article suggests that targeting specific immune pathways could help control and treat the skin disease hidradenitis suppurativa.
7 citations,
July 2022 in “Pharmaceuticals” Pumpkin Seed Oil in niosomes may help treat hair loss and improve hair growth.
3 citations,
January 2023 in “PloS one” Implanting hair-follicle stem cells in mice brains helped repair brain bleeding and reduced brain inflammation.
research Skin
2 citations,
January 2011 in “Elsevier eBooks” Skin problems are common in Lupus patients and can indicate the disease's severity, requiring specific treatments and lifestyle changes.
185 citations,
August 2020 in “Mayo Clinic Proceedings” Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.
65 citations,
March 2016 in “Lasers in Medical Science” Most low-level light therapy studies did not accurately report how light was measured, affecting treatment reliability.
39 citations,
June 2019 in “Toxins” Bee venom might be a good alternative treatment for various skin conditions because it has many healing properties.
25 citations,
December 2018 in “Human Molecular Genetics” The document concludes that certain mutations may contribute to the inflammation in hidradenitis suppurativa and suggests that targeting TNFα could be a treatment strategy.
22 citations,
March 2018 in “American Journal of Clinical Dermatology” New acne treatments show promise as alternatives to traditional therapies.
9 citations,
April 2021 in “Expert opinion on pharmacotherapy” Clascoterone is a new, effective, and safe acne treatment without systemic side effects.
5 citations,
March 2023 in “Archives of dermatological research” Increased HIF-1α is linked to the inflammation and severity of hidradenitis suppurativa, suggesting treatments that lower HIF-1α could help.
5 citations,
October 2020 in “Brain Research Bulletin” Etifoxine, an anxiety drug, can lessen brain inflammation and cognitive issues in mice, partly by increasing production of protective brain steroids.
research Acne
4 citations,
January 2019 Acne is a common skin condition that can be influenced by diet, lifestyle, and hormones, and requires a treatment approach that includes psychological considerations.
2 citations,
January 2011 in “Elsevier eBooks” The document reviewed various forms of acne and acneiform eruptions, their causes, symptoms, and treatments, emphasizing the importance of early intervention to prevent scarring and psychosocial impacts. It covered acne vulgaris, affecting 40-50 million people annually in the USA, and its persistence into adulthood, particularly in women. The pathogenesis involved factors like altered follicular keratinization and Propionibacterium acnes colonization. Treatments included topical retinoids, antibiotics, hormonal therapy, and isotretinoin, with considerations for pregnancy safety. The document also explored acne-associated syndromes and severe forms like acne conglobata, highlighting the psychological impact and treatment options such as isotretinoin and anti-inflammatory therapies. Additionally, it discussed rosacea, its subtypes, and management strategies, as well as the challenges of treating acne during pregnancy, recommending safer options like erythromycin and azelaic acid. The document emphasized the need for personalized treatment plans and further research to improve diagnostic criteria and management of acne and related conditions.
September 2023 in “Clinical, cosmetic and investigational dermatology” SLFC can improve scalp health and reduce sensitive scalp symptoms.
January 2019 in “ARC journal of pharmaceutical sciences” Acne can be managed with various treatments and requires psychological support due to its emotional impact.
January 2017 in “Springer eBooks” The document explains various skin conditions and their treatments.
January 2018 in “Springer eBooks” Hidradenitis Suppurativa is likely an autoinflammatory disease, and better understanding its causes could improve treatments.