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    Did you mean Pro-inflammatory cytokines?
    Glossary Pro-inflammatory cytokines

    signaling molecules that trigger inflammation in the body

    Pro-inflammatory cytokines are signaling molecules released by immune cells that promote inflammation in the body. They play a crucial role in the immune response by helping to fight off infections and heal injuries, but excessive or chronic production can lead to inflammatory diseases such as rheumatoid arthritis, psoriasis, and alopecia areata. Examples include tumor necrosis factor-alpha (TNF-α), interleukin-1 (IL-1), and interleukin-6 (IL-6).

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    1. Advanced glycation end-products inhibit mesenchymal-epidermal interaction by up-regulating proinflammatory cytokines in hair follicles European Journal of Dermatology · 2015 · 3 citations
    2. The effects of methylated flavonoids on depression-like activity and pro-inflammatory cytokine thresholds in mice induced by repeated finasteride administration European Journal of Inflammation · 2021 · 1 citations
    3. FC053 Pro-inflammatory cytokine cascade in human plucked hair 1997
    4. Proinflammatory cytokines regulate epidermal stem cells in wound epithelialization Stem Cell Research & Therapy · 2020 · 65 citations
    5. A new TH17 cytokine in hidradenitis suppurativa: antimicrobial and pro-inflammatory role of IL-26 2020
    6. Treatment with Light-Emitting Diodes of Wavelength 863 nm Delays DMBA/TPA-Induced Skin Tumor Formation and Decreases Proinflammatory Cytokine Levels in ICR Mice BioMed Research International · 2022 · 2 citations
    7. Epidermal keratinocytes initiate wound healing and pro-inflammatory immune responses following percutaneous schistosome infection 2015 · 39 citations
    8. Inflammatory perifollicular fibrosis and alopecia International Journal of Dermatology · 1998 · 10 citations
    9. Local anti-inflammatory effect and immunomodulatory activity of chitosan-based dressing in skin wound healing: a systematic review Journal of clinical and translational research · 2022 · 4 citations
    10. Alleviation of Androgenetic Alopecia with Aqueous Paeonia lactiflora and Poria cocos Extract Intake through Suppressing the Steroid Hormone and Inflammatory Pathway Pharmaceuticals · 2021 · 4 citations
    11. Possible Immunomodulating Effect of Retinol on Cytokines Secretion in Patients with Recurrent Furunculosis Archivum Immunologiae et Therapiae Experimentalis · 2017 · 4 citations
    12. Engineering a 3D wounded skin equivalent to study early inflammatory and regenerative responses in vitro Frontiers in Bioengineering and Biotechnology · 2025 · 1 citations
    13. Healthy individuals genetically at-risk for the development of Pemphigus vulgaris or Alopecia areata share disease-like cytokine dysregulation Frontiers in Immunology · 2025 · 1 citations
    14. The Anti-Muscle Atrophy Effects of Ishige sinicola in LPS-Induced C2C12 Myotubes through Its Antioxidant and Anti-Inflammatory Actions Applied sciences (Basel) · 2023 · 1 citations
    15. The high-polarity fraction of tail fat derived from Lanzhou Fat-Tailed sheep enhances skin wound healing through the regulation of inflammatory factors and the TGF-β1/Smad3 signaling pathway Food Science and Human Wellness · 2026
    16. A novel cell-penetrating peptide supports hair follicle growth through anti-inflammatory and growth factor–associated mechanisms in preclinical models BMC Biotechnology · 2026
    17. Iron-curcumin-carboxy PTIO coordinated nanoparticles with anti-inflammatory properties for enhanced diabetic wound healing Frontiers in Materials · 2026
    18. Oral Centella asiatica Extract Attenuates UVB-Induced Skin Photoaging via Antioxidant, Anti-Inflammatory, and Extracellular Matrix-Preserving Effects in Hairless Mice International Journal of Molecular Sciences · 2025
    19. Comprehensive Evaluation of <i>Tectona grandis</i> L.f.: Integrated <i>In Vitro</i> and <i>In Silico</i> Analysis of Steroid 5α-Reductase Inhibition and Anti-Inflammatory Properties ACS Omega · 2025
    20. Saponins of Paris polyphylla for the Improvement of Acne: Anti-Inflammatory, Antibacterial, Antioxidant and Immunomodulatory Effects 2024
    21. Extracellular vesicles released by hair follicle and adipose mesenchymal stromal cells induce comparable neuroprotective and anti-inflammatory effects in primary neuronal and microglial cultures Cytotherapy · 2023
    22. 708 SIG-1451: A topical anti-inflammatory new chemical entity for atopic dermatitis (AD) Journal of Investigative Dermatology · 2017
    23. 713 Fisetin promotes differentiation, inhibits proliferative and inflammatory responses in cultured human cells and alleviates psoriasiform dermatitis in mice Journal of Investigative Dermatology · 2017
    24. Air pollution and skin diseases: Adverse effects of airborne particulate matter on various skin diseases Life Sciences · 2016 · 295 citations
    25. Fibrous scaffolds potentiate the paracrine function of mesenchymal stem cells: A new dimension in cell-material interaction Biomaterials · 2017 · 182 citations
    26. Role of Cytotoxic T Cells in Chronic Alopecia Areata Journal of Investigative Dermatology · 2000 · 127 citations
    27. Updated Treatment for Acne: Targeted Therapy Based on Pathogenesis Dermatology and Therapy · 2021 · 78 citations
    28. What causes hidradenitis suppurativa ?—15 years after Experimental Dermatology · 2020 · 78 citations
    29. Dermatophytosis in companion animals: A review Veterinary World · 2020 · 69 citations
    30. Novel Fish Oil-based Bigel System for Controlled Drug Delivery and its Influence on Immunomodulatory Activity of Imiquimod Against Skin Cancer Pharmaceutical Research · 2016 · 56 citations