15 citations,
July 2021 in “Bosnian Journal of Basic Medical Sciences” Stem cell therapy is promising for treating various health conditions, but more research is needed to understand its full potential and address challenges.
7 citations,
August 2022 in “Experimental dermatology” Blocking YAP/TAZ could be a new way to treat skin cancer.
489 citations,
November 2021 in “Signal Transduction and Targeted Therapy” The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
6 citations,
June 2011 in “British Journal of Dermatology” People with alopecia areata have higher levels of RBP4 protein and antibodies against it.
610 citations,
April 2014 in “Nature Reviews Immunology” The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.
24 citations,
May 2012 in “International Journal of Dermatology” The document concludes that eyelash trichomegaly, which is the abnormal growth of eyelashes, can be present from birth, caused by diseases, or result from certain medications.
24 citations,
May 2009 in “Veterinary Dermatology” The document concludes that veterinary dermatologists need more experience and a better approach to treating skin diseases in nonhuman primates.
2 citations,
August 2016 in “Lasers in Surgery and Medicine” Photodynamic therapy can remove nonpigmented hair in mice and might work for humans.
1 citations,
January 2014 in “Elsevier eBooks” Melanocytes produce melanin; their defects cause vitiligo and hair graying, with treatments available for vitiligo.
1 citations,
October 2013 in “Expert Review of Dermatology” Diagnosing alopecia areata is challenging and requires careful examination and various tests to distinguish it from other hair loss types.
195 citations,
January 2008 in “Photochemistry and Photobiology” Visible light can damage skin and most sunscreens don't block it well; more research is needed on its effects and protection methods.
147 citations,
November 2020 in “International Journal of Molecular Sciences” Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.
94 citations,
June 2016 in “The FASEB Journal” The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.
25 citations,
January 2005 in “Pediatric Dermatology” Methotrexate effectively treated a 2-year-old's generalized pustular psoriasis without side effects.
21 citations,
January 2005 in “Pediatric Dermatology” An 8-year-old girl with vitiligo developed extra hair growth on her knee after using tacrolimus ointment.
20 citations,
October 2016 in “Veterinary dermatology” Dogs with generalized discoid lupus erythematosus have similar symptoms to humans and need continuous treatment.
16 citations,
January 2005 in “Pediatric Dermatology” A 10-year-old girl with Fox Fordyce disease improved with treatment, suggesting the disease can occur before puberty and might be underdiagnosed in young girls.
14 citations,
January 2005 in “Pediatric Dermatology” UVA1-light therapy successfully treated a child's skin condition, mycosis fungoides.
4 citations,
January 2021 in “Skin appendage disorders” Trichodynia is a painful scalp condition not directly linked to the amount or type of hair loss and may involve psychological factors, with treatments showing mixed results.
1 citations,
May 2023 in “Frontiers in medicine” Hair dyes and perms can damage hair and scalp, but using interventions can reduce harm.
1 citations,
January 2006 in “Elsevier eBooks” Cats lose fur due to various reasons, including allergies, infections, genetics, hormones, diet, cancer, stress, and some conditions are treatable while others are not.
July 2020 in “Research Square (Research Square)” Selective breeding can enhance immunity in dairy cattle.
179 citations,
October 2018 in “American Journal of Clinical Dermatology” Cancer treatments targeting specific cells and the immune system can cause skin, mouth, hair, and nail problems, affecting patients' quality of life and treatment adherence.
156 citations,
August 2016 in “Journal of controlled release” Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.
105 citations,
April 2004 in “Dermatologic Therapy” The document concludes that proper diagnosis and a combination of medical, hair-care, and surgical treatments are important for managing alopecia in black women.
103 citations,
December 2011 in “Journal of the American Academy of Dermatology” Chemotherapy often causes temporary hair loss, which is distressing and needs better treatment and support.
53 citations,
November 1992 in “Mayo Clinic Proceedings” HIV can cause unusual and severe skin problems that are hard to treat.
42 citations,
August 1999 in “The American journal of pathology” Basal cell carcinomas have much higher levels of Vitamin D3 receptors compared to healthy skin.
33 citations,
January 2018 in “The International Journal of Developmental Biology” Cell aging can be both good and bad for tissue repair.
10 citations,
January 2023 in “Acta dermato-venereologica” Baricitinib and deuruxolitinib are effective for treating alopecia areata, but their efficacy depends on the dose.