Hair And Nails: A Review Of Recent Studies

    May 2009 in “ Medical and surgical dermatology/Medical & surgical dermatology ”
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    TLDR Hair and nail conditions can stabilize or improve over time, and new treatments show promise.
    The document reviewed several studies related to hair and nails. One study on frontal fibrosing alopecia (FFA) found that the condition, more common in postmenopausal women, often stabilized over time with or without treatment. Another study showed that the tripeptide K(D)PT could stimulate hair pigmentation under proinflammatory conditions, suggesting potential as an antigreying agent. A study on acute diffuse and total alopecia (ADTA) identified it as a new subtype of alopecia areata with a favorable prognosis, showing rapid and spontaneous hair regrowth within 6 months. Additional research highlighted the role of primary cilia in hair follicle morphogenesis and the involvement of transglutaminase-3 in hair shaft scaffolding. Lastly, a study on Mohs micrographic surgery demonstrated high concordance between surgeons and dermatopathologists in interpreting frozen sections, with a 99.7% agreement rate.
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