October 2024 in “Skin Appendage Disorders” This bibliometric analysis reported that PRP is most frequently studied for hair restoration, especially in placebo-controlled trials, although differences in PRP preparation and outcome measures challenge result consistency across studies.
9 citations
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September 2017 in “Journal of Investigative Dermatology Symposium Proceedings” In this study, PGD2 was shown to increase testosterone production in human keratinocytes through reactive oxygen species, suggesting potential benefits of antioxidants like N-acetyl-cysteine for AGA patients.
February 2017 in “Spectrum Research Repository (Concordia University)” This study confirmed porcine PRP's commercial viability as a fetal bovine serum replacement, showing higher growth factor levels and stability, without increasing human follicle dermal papilla cell proliferation compared to FBS.
January 2025 in “Journal of Plastic Reconstructive & Aesthetic Surgery” Two L-PRP treatments improve hair density in mild to moderate alopecia.
6 citations
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September 2021 in “AESTHETIC OROFACIAL SCIENCE” This review discusses the cost-effectiveness and potential benefits of platelet-rich plasma for facial dermal rejuvenation but reports no new clinical results.
76 citations
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December 2018 in “Aesthetic Plastic Surgery” This review discusses various aesthetic and regenerative applications of platelet-rich plasma and concludes that it has potential as a safe cosmetic intervention but requires further studies to understand its clinical effects.
September 2023 in “Journal of Education, Health and Sport” This review examines the potential uses of platelet-rich plasma in dermatology, noting its growing therapeutic applications, but highlights the need for more standardized procedures and larger studies to confirm its effects.
16 citations
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January 2018 in “Dermatology Online Journal” This review discusses platelet-rich plasma treatment for androgenic alopecia, summarizing current understanding of the disease and the need for standardized clinical trials, but it reports no new results.
4 citations
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October 2019 in “Acta Médica Costarricense” This study highlights that while platelet-rich plasma is showing promise across multiple medical fields like dentistry and sports medicine, a lack of standardized protocols and robust clinical trials limits its routine clinical application.
4 citations
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September 2024 in “PubMed” This review discusses the efficacy and safety of platelet-rich plasma for facial rejuvenation but reports no definitive clinical results, noting the evidence remains insufficient for firm conclusions.
73 citations
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June 2001 in “Endocrinology” In this study, researchers found that disrupting the PRL gene in mice led to earlier hair molting, especially in females, suggesting that PRL inhibits murine hair cycle events.
1 citations
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July 2019 in “Small ruminant research” This study suggests that the NGF/TrkA/CREB system plays a crucial role in promoting outer root sheath cell proliferation in cashmere goats, which may aid in marker-assisted breeding.
5 citations
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November 2021 in “Journal of Plastic Reconstructive and Aesthetic Surgery” This study found that platelet-rich plasma was safe and effective for treating female androgenetic alopecia, presenting a promising alternative to traditional medications like Minoxidil® and Finasteride®.
January 2025 in “Fìzìologìčnij žurnal” This study found that in patients with elevated fibrinogen levels undergoing revision rhinoplasty, PDRN decreased M1 cytokines and increased M2 cytokines, potentially offering a new therapeutic approach, but further research is needed to understand its mechanisms and effects fully.
2 citations
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April 2014 in “PubMed” Platelet Rich Plasma (PRP) shows promise for hair growth, ulcer healing, and skin rejuvenation, but more research is needed for consistent results and it's not suitable for people with certain blood conditions.
7 citations
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October 2024 in “Cells” This review discusses the potential of platelet-rich plasma in regenerative medicine and aging-related diseases but notes that clinical efficacy remains unclear due to varying study results and preparation inconsistencies.
This lecture presented the author's experience with over 250 PRP treatments on more than 150 patients in esthetic dermatology, highlighting PRP's use of autologous platelets to potentially accelerate healing through normal pathways.
14 citations
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October 2017 in “European Journal of Medical Research” In this study, platelet-rich plasma injections in mice promoted hair growth and angiogenesis compared to control, as evidenced by longer hair lengths and increased vessel formation.
April 2018 in “Journal of Investigative Dermatology” This review discusses recent studies on platelet-rich plasma (PRP) therapy for androgenic alopecia and found varied results; the authors highlight a need for more controlled trials to standardize treatment methods.
December 2022 in “Journal of Pakistan Association of Dermatologists” In this study, PRP treatment for scalp hair restoration, combined with finasteride and minoxidil, resulted in reduced hair fall, stronger hair, and satisfactory regrowth in patients, with a satisfaction level of up to 90%.
January 2018 in “Journal of Visualized Experiments” This study found that injections of autologous platelet-rich plasma in patients with pattern hair loss were compared to placebo, but the abstract does not report specific clinical results.
25 citations
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May 2014 in “Facial Plastic Surgery” In this study, intradermal injections of autologous platelet-rich fibrin matrix significantly increased hair density in patients with androgenetic alopecia at 2 and 3 months after initial treatment.
1 citations
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January 2021 This review covers the use of platelet-rich plasma in dermatology for wound healing, hair restoration, skin rejuvenation, and dermal augmentation, and notes the need for standardized guidelines.
28 citations
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March 2020 in “Journal of ethnopharmacology” This study found that ginsenoside Rb1 treatment significantly reduced aging symptoms in mice by regulating cell cycle and apoptotic pathways, potentially linked to metabolic changes.
1 citations
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September 2024 in “Frontiers in Cell and Developmental Biology” This study found that platelet-rich fibrin provides more sustained therapeutic effects than platelet-rich plasma in inhibiting apoptosis and enhancing proliferation and migration of human endometrial stromal cells.
January 2015 in “Spectrum Research Repository (Concordia University)” This study confirmed that porcine platelet-rich plasma could commercially replace fetal bovine serum due to its higher growth factor levels and effectiveness as a hair growth promoter comparable to existing serum.
April 2024 in “Journal of cosmetic dermatology” This article discusses the development of liquid platelet-rich fibrin as a potential improvement over platelet-rich plasma for treating androgenetic alopecia and reports no new clinical results.
January 2026 in “Industrial Crops and Products” In this study, oral administration of ginsenoside Rf from Panax ginseng promoted hair regrowth and increased hair thickness in a mouse model of androgenetic alopecia by enhancing androgen receptor degradation, highlighting its potential for cosmetic and functional food applications.
2 citations
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June 2021 in “Cosmoderma” This article reviews the use of platelet-rich plasma (PRP) in various dermatological conditions and reports no new clinical results; the authors emphasize its efficacy and call for continued careful use.