Platelet Rich Plasma in Androgenic Alopecia: Where Do We Stand?

In 2014, there was growing interest in the use of Platelet Rich Plasma (PRP) in dermatology, particularly for androgenic alopecia, chronic ulcer healing, and skin rejuvenation. The evidence supporting PRP's effectiveness varied from low to medium, with the need for more well-defined double-blind or split-face trials. The procedure's frequency and preparation methods varied, but a monthly procedure for three months was deemed appropriate for hair growth. Optimal results were achieved with a platelet concentration four to five times the normal count. PRP also showed promising results in ulcer healing and as an adjuvant to fractional laser therapy in skin rejuvenation. However, monotherapy with PRP had yet to consistently show good results. Precautions were necessary to avoid infection and ensure consistent results, and the procedure was contraindicated for patients with bleeding disorders, platelet dysfunction syndrome, or those on anticoagulant therapy.