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Age, smoking, and lower BMI increase facial wrinkles; men wrinkle more than women, except in old age; pale skin and certain hormonal factors can protect against wrinkles.

No strong genetic link to other skin conditions was found, but some genetic factors may make people more likely to get seborrheic dermatitis.

Genetic differences within ethnic groups may affect prostate cancer treatment effectiveness.

A postmenopausal woman's increased male hormone levels were successfully treated with surgery.

High-dose corticosteroids and methotrexate had a modest effect on severe childhood alopecia, but side effects and relapse were concerns.

The African spiny mouse heals skin without scarring due to different protein activity compared to the common house mouse, which heals with scarring.

Testosterone and dihydrotestosterone have similar effects on body composition and metabolic health in men.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

Negative expectations can cause adverse effects in patients even without active treatment, and managing this nocebo effect involves better communication and patient-clinician relationships.

The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.

The document concludes that there are various treatments for different types of alopecia, but more research is needed for evidence-based treatments.

Pioglitazone usually doesn't effectively treat or cure lichen planopilaris.

Diagnose and manage CCCA with thorough history, exams, and labs; treat with anti-inflammatory agents, stress reduction, and stopping harmful hair practices.

Particle properties affect drug retention and release in minoxidil foams, with lipid nanoparticles having higher loading capacity.

Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.

Diabetes often causes various skin problems and complications.

Minoxidil dissolves better in ethanol-water mixtures at different temperatures, with water playing a key role.

Lower lipin 1β in belly fat is linked to insulin resistance in people with polycystic ovary syndrome.

Brazilian propolis was found to speed up hair growth in mice by increasing the growth of skin cells that form hair.

Increased HSD11B1 enzyme expression is linked to higher body fat and insulin resistance.

CBG may help with various medical conditions but needs more human research to confirm safety and effectiveness.

Acne is caused by multiple factors including oil production, bacteria, inflammation, and possibly diet and environment.

Psoriasis lesions have fewer and smaller oil glands, which might affect the condition's development.

Successful eyebrow restoration can be done using careful hair transplant techniques and choosing the right patients.

Asian patients with Frontal Fibrosing Alopecia often lose eyebrow hair and respond well to combined antiandrogen or antimalarial and topical treatments.

Western diet may cause male pattern baldness; low glycemic diet with magnesium could help.