Treatment-Refractory Central Centrifugal Cicatricial Alopecia Responsive to a Novel Botanical Treatment

    Sanusi Umar, Petrina Kan, Marissa J. Carter, Paul Shitabata
    Studysummary In this case series, four African American women with treatment-resistant central centrifugal cicatricial alopecia showed scalp itch relief and significant hair regrowth after using a new botanical formula for 8 weeks to 1 year, with no adverse effects reported.
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    Research cited in this study 14

    1. A Multimodal Hair-Loss Treatment Strategy Using a New Topical Phytoactive Formulation: A Report of Five Cases Case reports in dermatological medicine · 2021
    2. The Use of Natural Ingredients in the Treatment of Alopecias with an Emphasis on Central Centrifugal Cicatricial Alopecia: A Systematic Review PubMed · 2020
    3. Hair Regrowth in Two Patients with Recalcitrant Central Centrifugal Cicatricial Alopecia After Use of Topical Metformin JAAD Case Reports · 2020
    4. Variant PADI3 in Central Centrifugal Cicatricial Alopecia The New England Journal of Medicine · 2019
    5. Current and Emerging Treatment Strategies for Hair Loss in Women of Color International Journal of Women's Dermatology · 2019
    6. Lichen Planopilaris with Koebner Phenomenon JAAD Case Reports · 2018
    7. Fibroproliferative Genes Are Preferentially Expressed in Central Centrifugal Cicatricial Alopecia Journal of The American Academy of Dermatology · 2018
    8. Vitamin D Status in Scarring and Nonscarring Alopecia Journal of The American Academy of Dermatology · 2018
    9. Adipose and Hair Function: An Apparent Connection Journal of Investigative Dermatology · 2018
    10. Central Centrifugal Cicatricial Alopecia: Challenges and Solutions Clinical, Cosmetic and Investigational Dermatology · 2016
    11. Nutritional Influence on Hair Growth Aktuelle Dermatologie · 2011
    12. Lichen Planopilaris Treated With a Peroxisome Proliferator-Activated Receptor Gamma Agonist Archives of dermatology · 2009
    13. Central Centrifugal Cicatricial Alopecia: Past, Present, and Future Journal of The American Academy of Dermatology · 2009
    14. A Multicenter, Randomized, Placebo-Controlled, Double-Blind Clinical Trial of a Novel Formulation of 5% Minoxidil Topical Foam Versus Placebo in the Treatment of Androgenetic Alopecia in Men Journal of The American Academy of Dermatology · 2007