research A Powerful Method for Pleiotropic Analysis Under Composite Null Hypothesis Identifies Novel Shared Loci Between Type 2 Diabetes and Prostate Cancer
New method finds genetic links between Type 2 Diabetes and Prostate Cancer not seen before.
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660-690 / 729 results research Canine Follicle Stem Cell Candidates Reside in the Bulge and Share Characteristic Features with Human Bulge Cells
Canine hair follicles have stem cells similar to human hair follicles, useful for studying hair disorders.
research Ligand-Independent Actions of the Vitamin D Receptor: More Questions Than Answers
The vitamin D receptor can act without its usual activating molecule, affecting hair growth and skin cancer, but its full range of actions is not well understood.
research Autophagy Protects Murine Preputial Glands Against Premature Aging and Controls Their Sebum Phospholipid and Pheromone Profile
Autophagy prevents early aging and maintains lipid and pheromone balance in mouse glands.
research Human Biallelic MFN2 Mutations Induce Mitochondrial Dysfunction, Upper Body Adipose Hyperplasia, and Suppression of Leptin Expression
MFN2 mutations cause mitochondrial problems, leading to more upper body fat and lower leptin levels.
research Time-Course RNA-Seq Analysis Reveals Stage-Specific and Melatonin-Triggered Gene Expression Patterns During the Hair Follicle Growth Cycle in Goats
Melatonin affects different genes and pathways important for goat hair growth.
research Decision Letter: Human Biallelic MFN2 Mutations Induce Mitochondrial Dysfunction, Upper Body Adipose Hyperplasia, and Suppression of Leptin Expression
MFN2 mutations cause mitochondrial problems, unusual fat distribution, and low leptin despite high body fat.
research Advanced Inhibition of Undesired Human Hair Growth by PPARγ Modulation
GMG-43AC may help reduce unwanted hair growth and treat certain hair loss conditions.
research The PPAR-γ Modulator, N-Acetyl-GED, Protects From Epithelial-Mesenchymal Transition in Human Hair Follicles: Potential Relevance for Scarring Alopecia
N-acetyl-GED may help prevent and partially reverse a process that leads to scarring hair loss.
research Peroxisome Proliferator-Activated Receptor-γ Signalling Protects Hair Follicle Stem Cells from Chemotherapy-Induced Apoptosis and Epithelial-Mesenchymal Transition
Activating PPAR-γ signalling can protect hair follicle stem cells from damage caused by chemotherapy.
research Influence of Substance P on Cultured Sebocytes
Substance P may worsen acne by increasing inflammation, but corticosteroids might help by reducing this effect.
research Cicatricial Alopecia Symposium 2011: Lipids, Inflammation, and Stem Cells
The symposium concluded that a specific lipid might cause hair loss, inflammation is a key factor, and stem cells in bald scalps aren't working right, suggesting new treatment targets.
research Lichen Planopilaris: Mechanisms, Subtypes, and Diagnosis
Lichen planopilaris causes permanent hair loss and scarring due to damage to hair follicles and can be mistaken for other hair loss conditions.
research Inhibition of Cholesterol Biosynthesis Modulates Epithelial-Mesenchymal Transition in Primary Cicatricial Alopecia Through TGFβ and Angiotensin Receptors
Blocking cholesterol production may help control hair loss in Primary Cicatricial Alopecia by affecting key regulators.
research Long Non-Coding RNA AL136131.3 Inhibits Hair Growth Through Mediating Glycolysis in Androgenetic Alopecia
The RNA AL136131.3 slows down hair growth and speeds up hair loss by affecting sugar breakdown in hair follicles.
research Epithelially Derived MPZL3 Negatively Regulates Murine and Human Sebaceous Gland Size and Sebocyte Proliferation
MPZL3 protein helps control the size of oil glands and the growth of oil-producing cells in both mice and humans.
research Graham-Little Piccardi Lassueur Syndrome and Review of the Literature
Graham-Little Piccardi Lassueur Syndrome is a rare skin condition with specific hair loss and skin symptoms.
research Skin Fibroblast Heterogeneity and Plasticity Are Determined by the Local Niche
Mouse skin fibroblasts vary in function and adaptability based on their environment.
research Folliculocentric Papules and Alopecia in a 70-Year-Old Woman Diagnosed with Graham-Little-Piccardi-Lassueur Syndrome
A 70-year-old woman with a rare skin condition improved after treatment with topical steroids and acitretin.
research Dialogues in Dermatology: Highlights from 2011
2011 dermatology discussions highlighted stem cell hair treatments, new lichen planopilaris therapies, skin side effects from cancer drugs, emerging allergens, and the link between food allergies and skin issues.
research Long Non-Coding RNA AL136131.3 Inhibits Hair Growth Through Mediating Glycolysis in Androgenetic Alopecia
AL136131.3 slows hair growth by affecting energy processes in hair loss.
research Jieduquyuziyin Prescription Alleviates SLE Complicated by Atherosclerosis via Promoting Cholesterol Efflux and Suppressing TLR9/MyD88 Activation
Jieduquyuziyin prescription helps treat SLE with atherosclerosis by improving cholesterol removal and reducing inflammation.
research Lichen Planopilaris Treated by the Peroxisome Proliferator-Activated Receptor-γ Agonist Pioglitazone: Lack of Lasting Improvement or Cure in the Majority of Patients
Pioglitazone usually doesn't effectively treat or cure lichen planopilaris.
research Hair India 2010: First International Conference by Hair Research Society of India
The Hair India 2010 conference introduced a new hair loss classification and highlighted advanced diagnostic techniques in trichology.
research Platelet-Rich Plasma for the Treatment of Androgenetic Alopecia: A Patient Survey
PRP treatment for hair loss shows promise, with 58% of patients satisfied and most noticing improvement within 6 months.
research Placebo Controlled Clinical Evaluation of a Topical Moisturizer Formula Containing Phytol
The moisturizer with phytol improved skin texture and reduced fine wrinkles better than the moisturizer without it.
research Repurposing of Linagliptin and Similar FDA Approved Drugs as Antidiabetic Agents
Pranlukast and mirabegron may work as new diabetes drugs.
research Pityriasis Rubra Pilaris Unveiling a Case of New Onset Hepatitis C Infection
A woman with a skin disorder was found to have hepatitis C, which may be linked, and was safely treated with methotrexate.
research PLAU and SerpinB2 Role in Apoptosis in Leprosy
PLAU and SerpinB2 affect cell death differently in various forms of leprosy and could be targets for new treatments.
research Increasing Mupirocin Resistance in Pediatric Methicillin-Resistant Staphylococcus Aureus Skin and Soft-Tissue Infections in New York: A Genomic Approach
There's a growing resistance to the antibiotic mupirocin in children's skin infections caused by MRSA in New York.