Pityriasis Rubra Pilaris Unveiling a Case of New Onset Hepatitis C Infection

May 2017 in “ Journal of The American Academy of Dermatology ”

androgenetic alopecia platelet-rich plasma methotrexate PRP

TLDR A woman with a skin disorder was found to have hepatitis C, which may be linked, and was safely treated with methotrexate.

The document reports on a case of a 41-year-old woman who was initially misdiagnosed with psoriasis but was later correctly diagnosed with Pityriasis rubra pilaris (PRP), a papulosquamous disorder. During her evaluation, she was found to have a new onset hepatitis C infection, despite testing negative for it the previous year. The patient was treated with methotrexate, which improved her skin lesions and resolved her mild transaminitis. The case suggests a potential association between hepatitis C and PRP and demonstrates that methotrexate can be used safely in a patient with hepatitis C under close monitoring. The document also includes other unrelated studies, such as a clinical evaluation of a topical moisturizer containing phytol and a patient survey on the treatment of androgenetic alopecia with platelet-rich plasma (PRP), but these are not related to the main case report on PRP and hepatitis C.

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