Increasing Mupirocin Resistance in Pediatric Methicillin-Resistant Staphylococcus Aureus Skin and Soft-Tissue Infections in New York: A Genomic Approach

    May 2015 in “ Journal of The American Academy of Dermatology ”
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    TLDR There's a growing resistance to the antibiotic mupirocin in children's skin infections caused by MRSA in New York.
    The document discusses three separate studies. The first study, involving 35 patients with psoriasis and 32 healthy subjects, found that blood microarray biomarkers could potentially predict treatment response in individual patients. The second study, which analyzed 239 samples from pediatric patients with methicillin-resistant Staphylococcus aureus (MRSA) skin and soft-tissue infections, found that the prevalence of mupirocin resistance in MRSA had increased over recent years, possibly due to the spread of the mupA plasmid. The third study demonstrated that new hair regeneration could be achieved by cultured adult cells, potentially offering a solution for hair loss. The study used adult dermal papilla cells as an instructive feeder to guide the differentiation of cultivated adult keratinocytes, which were then able to produce new hair fibers.
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