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This study found that nanocapsules formulated as a dispersion and applied with massage may enhance follicular uptake of clobetasol propionate while minimizing its skin penetration, offering a potential improvement over conventional treatments for scalp diseases.

This study suggests that a sandwich-structured wound dressing with bioceramic and polylactic acid layers may improve burn wound healing by absorbing exudates and promoting hair follicle regeneration.

This study found that targeting the hair follicle can be increased by using lipophilic drugs combined with surfactant solutions and propylene glycol.

In this study, the researchers reported that chloramphenicol-loaded liposomes, particularly those incorporating deoxycholic acid, enhanced follicular uptake and showed strong antibacterial activity against methicillin-resistant Staphylococcus aureus, offering potential for treating MRSA-infected skin conditions with good skin biocompatibility and minimal toxicity.

This study found that nanoemulsion formulations with oleic acid or eucalyptol significantly enhanced the delivery and retention of caffeine through hair follicles and surrounding skin regions.

This study found that polymers significantly improved the chemical and microbial stability of steroid hormones in liposome formulations over eight weeks, with finasteride showing the highest diffusion rate.

This article explains the preparation methods and applications for various vesicle and particle systems used in transdermal drug delivery, highlighting their effectiveness and potential for further development in this field.

This study found that biodegradable PLA particles released fluorochromes in a time-dependent manner on human skin, with BP-PLA particles releasing rapidly and DiAsp-PLA particles providing sustained release and accumulation in hair follicles.

In this study, researchers reviewed recent advances in using nanoencapsulation technology to improve the pharmacological treatment of alopecia, suggesting its potential to enhance drug delivery and reduce adverse effects compared to conventional methods.

This review discusses the pharmacological actions of mangiferin and the potential of delivery carriers to overcome its limitations, but reports no new clinical results.

Non-viral vectors show promise for safe and effective CRISPR/Cas9 gene editing in treating diseases.

In this study, fraction No. 3 of Oryza sativa bran extract demonstrated high unsaturated fatty acid content and significant 5α-reductase inhibition, suggesting potential for developing anti-androgenic alopecia products.

This review discusses how polymer-based nanocarriers can enhance drug delivery targeting hair follicles for acne treatment, focusing on factors affecting this delivery method, combination technologies to improve follicle targeting, and recent advancements in polymer nanodrug-delivery systems.

This review explains the mechanical composition and molecular interactions that determine hair's mechanical properties, without providing any new experimental findings.

This review discusses advances in drug delivery systems to enhance oleanolic acid's bioavailability and therapeutic potential but reports no new clinical results.

This study found that arginine-loaded lipidic nanoparticles improved hair follicle growth in male hamsters more effectively than an aqueous arginine solution.

This study found that hair absorbs significant amounts of NaBr from solution, with absorption increasing linearly with solution concentration and additional effects noted with acidic or basic solutions.

In this study, a hydrogel with anti-inflammatory, antibacterial, antioxidant, and wound tissue adhesion properties was developed, showing significant potential for wound healing and suggesting it could offer a new and effective treatment option in clinical settings.

This article discusses how challenges in drug development and success rates are driving a shift in the pharmaceutical industry towards engineering targeted drug delivery systems, with nanomaterials offering potential solutions for selective therapeutic delivery.

This study demonstrated that using PLGA nanoparticles to deliver chlorogenic acid significantly increased type 17 collagen production in human epidermal cells, indicating potential for improved skincare formulations.

In this study, HA-P5, a nanoparticle derived from peptide and polysaccharide conjugation, effectively reduced acne lesions and sebum production by inhibiting specific receptors in cells, without triggering unfavorable reactions compared to a commercial inhibitor, highlighting HA-P5's potential as a novel acne treatment.

This study found that injectable finasteride microspheres provided a sustained drug release with a minimal initial burst in albino rabbits compared to oral suspension.

This review explores nano-quercetin formulations to enhance the solubility, stability, and targeted delivery of quercetin, highlighting its potential efficacy in treating cancer, inflammation, metabolic diseases, and tissue regeneration, though challenges in biocompatibility, toxicity, and production remain, per this source.

This study found that spanlastic gel loaded with thymoquinone and ascorbic acid improved skin deposition and tyrosinase inhibition, suggesting potential as a treatment for hyperpigmentation.

In this study, researchers developed hyaluronic acid derivatives functionalized with nitric oxide photodonors for light-activated skin treatments, finding that the compounds released NO under blue light and enhanced keratinocyte proliferation and migration, suggesting potential for therapeutic use.

This study concluded that a liquid serum formulation delivered two fluorescent dyes to deeper follicular regions more effectively than nanoparticle systems.

This review discusses the roles of hair follicles and sebaceous glands in percutaneous transport and reports no new results, noting a lack of adequate models and methodologies.

This review highlights novel drug delivery systems for alopecia that enhance localization in the pilosebaceous unit, reduce systemic exposure, and support sustained drug release, with a focus on optimized follicular carriers ranging from 100-300 nm for improved drug residence compared to conventional methods.

In this review, researchers discussed various novel drug delivery systems, including lipid nanocarriers and polymeric nanoparticles, that may enhance treatment for alopecia by improving drug localization in hair follicles and reducing systemic exposure, potentially offering better outcomes than conventional treatments.

This review explores the potential of herbal therapies and modern delivery methods for managing premature hair greying, highlighting promising plant-based treatments and emphasizing the need for clinical trials to validate their effectiveness.