Anti-MRSA Malleable Liposomes Carrying Chloramphenicol for Ameliorating Hair Follicle Targeting

    November 2017 in “ International journal of nanomedicine ”
    Chih‐Cheng Hsu, Shih-Chun Yang, Ching-Hwa Sung … Jia‐You Fang
    Studysummary In this study, the researchers reported that chloramphenicol-loaded liposomes, particularly those incorporating deoxycholic acid, enhanced follicular uptake and showed strong antibacterial activity against methicillin-resistant Staphylococcus aureus, offering potential for treating MRSA-infected skin conditions with good skin biocompatibility and minimal toxicity.
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    Research cited in this study 6

    1. Anti-PDGF Receptor β Antibody-Conjugated Squarticles Loaded with Minoxidil for Alopecia Treatment by Targeting Hair Follicles and Dermal Papilla Cells Nanomedicine: Nanotechnology, Biology and Medicine · 2015
    2. Erbium-Yttrium-Aluminum-Garnet Laser Irradiation Ameliorates Skin Permeation and Follicular Delivery of Antialopecia Drugs Journal of Pharmaceutical Sciences · 2014
    3. Delivery and Targeting of Nanoparticles into Hair Follicles Therapeutic Delivery · 2014
    4. Targeted Delivery of a Poorly Water-Soluble Compound to Hair Follicles Using Polymeric Nanoparticle Suspensions International journal of pharmaceutics · 2011
    5. Enhancement of Follicular Delivery of Finasteride by Liposomes and Niosomes International Journal of Pharmaceutics · 2006
    6. Innovative Liposomes as a Transfollicular Drug Delivery System: Penetration into Porcine Hair Follicles Journal of Investigative Dermatology · 2006