25 citations
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July 2020 in “Journal of cosmetic dermatology” In this study, the authors reported that while deoxycholic acid effectively reduces submental fat, it can cause adverse effects such as edema, numbness, and skin necrosis, making knowledge of possible complications essential for clinicians.
17 citations
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August 2019 in “JAMA Facial Plastic Surgery” This letter to the editor reports an observation of alopecia occurring after treatment with deoxycholic acid for reducing submental fat, but it presents no new clinical data or broader conclusions.
7 citations
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September 2018 in “Aesthetic surgery journal” This study found that deoxycholic acid effectively reduces excess fat under the chin, showing significant volume reduction and increased patient satisfaction in both aesthetic improvements and recovery experiences among the 13 participants.
5 citations
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January 2024 in “Aesthetic Surgery Journal Open Forum” This review notes that while ATX-101 showed a favorable safety profile for reducing submental fat in clinical trials, serious adverse events related to procedures have been reported in real-world use, prompting recommendations for improved management and prevention strategies.
1 citations
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February 2023 in “Russian Journal of Bioorganic Chemistry” In an animal study, researchers observed that a newly synthesized deoxycholic acid derivative showed similar prostate protection effects to finasteride in Wistar rats while being less toxic.