research Dermal Adipocyte Lipolysis and Myofibroblast Conversion Are Required for Efficient Skin Repair
Fat cells in the skin help start healing and form important repair cells after injury.
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research First Use of Thymus Transplantation Therapy for FOXN1 Deficiency (Nude/SCID): A Report of 2 Cases
Thymus transplantation successfully restored immune function in infants with FOXN1 deficiency.
research Maternal PPARγ Protects Nursing Neonates by Suppressing the Production of Inflammatory Milk
A mother's PPARγ is crucial for preventing harmful milk that can cause inflammation and growth problems in babies.
research Human Hair Follicles Are an Extrarenal Source and a Nonhematopoietic Target of Erythropoietin
Human hair follicles produce and respond to erythropoietin, helping protect against stress.
research Characterization of Hair Follicle Development in Engineered Skin Substitutes
Engineered skin substitutes can grow hair but have limitations like missing sebaceous glands and hair not breaking through the skin naturally.
research Cystathionine Beta-Synthase-Deficient Mice Thrive on a Low-Methionine Diet
Mice with CBS deficiency are healthier on a low-methionine diet.
research The CD44+ALDH+ Population of Human Keratinocytes Is Enriched for Epidermal Stem Cells with Long-Term Repopulating Ability
Certain human skin cells marked by CD44 and ALDH are rich in stem cells capable of long-term skin renewal.
research Gene Expression of Type 2 17β Hydroxysteroid Dehydrogenase in Scalp Hairs of Hirsute Women
Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.
research Flightless I Exacerbation of Inflammatory Responses Contributes to Increased Colonic Damage in a Mouse Model of Dextran Sulfate Sodium-Induced Ulcerative Colitis
High levels of the protein Flightless I worsen ulcerative colitis symptoms in mice.
research Cutaneous Lupus Erythematosus Presenting as Frontal Fibrosing Alopecia: Report of 2 Patients
Two patients with skin lupus were mistakenly thought to have a different scalp condition but improved with lupus treatment.
research Vascular Endothelial Growth Factor Protects CD200-Rich and CD34-Positive Hair Follicle Stem Cells Against Androgen-Induced Apoptosis Through the Phosphoinositide 3-Kinase/Akt Pathway in Patients With Androgenic Alopecia
A substance called Vascular Endothelial Growth Factor can protect certain hair follicle stem cells from damage caused by androgens, suggesting a new possible treatment for hair loss.
research Photoprotective and Immunoregulatory Capacity of Ginsenoside Rg1 in Chronic Ultraviolet B-Irradiated BALB/c Mouse Skin
Ginsenoside Rg1 protects mouse skin from UVB damage and helps control inflammation.
research Safety of Whole-Body Abrogation of the TRF1 Shelterin Protein in Wild-Type and Cancer-Prone Mouse Models
Deleting the Trf1 protein in mice is safe and may help prevent cancer without major side effects.
research Androgenic Modulation of Arterial Baroreceptor Dysfunction and Neuroinflammation in Endotoxic Male Rats
Testosterone affects blood pressure control and inflammation in male rats with endotoxic shock, and blocking certain hormones may help treat it.
research Lupus Erythematosus and the Skin
Lupus affects the skin in various ways, and proper skin examination is crucial for diagnosis and treatment.
research Application of Second Near Infrared Fluorescence Imaging to Trace CelTrac1000-Labeled Hair Follicle Epidermal Neural Crest Stem Cells in Repairing Rat Facial Nerve Defects
NIR-II imaging effectively tracked stem cells that helped repair facial nerve defects in rats.
research Dermal Niche Signaling and Epidermal Stem Cells
Skin health and repair depend on the signals between skin stem cells and their surrounding cells.
research Tebentafusp-Tebn (Kimmtrak®) for HLA-A*02:01-Positive Unresectable or Metastatic Uveal Melanoma
Tebentafusp-tebn improves survival rates in uveal melanoma patients but has common side effects like rash and fatigue.
research Progression of Pseudolymphoma to True Cutaneous Lymphoma: Possible Role of Platelet-Rich Plasma (PRP), A Case Report
PRP treatments and hair transplantation may be linked to the progression of pseudolymphoma to lymphoma.
research Cyclin D3 Deficiency Inhibits Skin Tumor Development But Does Not Affect Normal Keratinocyte Proliferation
Lacking cyclin D3 reduces skin cancer growth without affecting normal skin cell growth.
research The Catalog of Human Hair Keratins
Human hair is made up of different keratins, some strong and some weak, with specific types appearing at various stages of hair growth.
research Visualizing Androgen Receptor Activity in Male and Female Mice
Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.
research MHC Class I-Like MILL Molecules Are β2-Microglobulin-Associated, GPI-Anchored Glycoproteins That Do Not Require TAP for Cell Surface Expression
MILL molecules are unique immune proteins in mice that don't need TAP to appear on cell surfaces.
research The Importance of Basonuclin 2 in Adult Mice and Its Relation to Basonuclin 1
Basonuclin 2 is vital for the development of facial bones, hair follicles, and male germ cells in adult mice, and its absence can lead to dwarfism and abnormal follicles.
research Thymic Stromal Lymphopoietin Controls Hair Growth
Thymic stromal lymphopoietin (TSLP) promotes hair growth, especially after skin injury.
research Immunohistochemical, Pharmacovigilance, and Omics Analyses Reveal the Involvement of ATP-Sensitive K+ Channel Subunits in Cancers: Role in Drug-Disease Interactions
ATP-sensitive K+ channel subunits, particularly Sur2A, play a significant role in various cancers.
research Cellular Therapeutics and Immunotherapies in Wound Healing – On the Pulse of Time?
Cellular and immunotherapies show promise for healing chronic wounds but need more research.
research Circulating and/or Cutaneous Irisin Resistance: A Novel Link Among Androgenetic Alopecia, Comorbid Metabolic Syndrome and Cardiovascular Risks
Androgenetic alopecia is linked to higher cardiovascular and metabolic risks, possibly due to irisin resistance.
research Pharmacokinetics, Toxicity, and Activity of Intravenous Dextran Sulfate in Human Immunodeficiency Virus Infection
Dextran sulfate was found to be toxic and ineffective for treating HIV.
research Lichen Planus – A Refractory Autoimmune Disorder
Lichen planus is a chronic autoimmune disease that is hard to treat and more common in women.