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    Glossary Polyamines

    organic compounds crucial for cell growth and function

    Polyamines are organic compounds that play a crucial role in cell growth and function. They are involved in various biological processes, including DNA stabilization, protein synthesis, and cell proliferation. In the context of hair, polyamines like spermidine have been shown to promote hair growth and may help in treating conditions like alopecia.

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    Research 30 of 415

    1. Activation of Polyamine Catabolism Profoundly Alters Tissue Polyamine Pools and Affects Hair Growth and Female Fertility in Transgenic Mice Overexpressing Spermidine/SpermineN 1-Acetyltransferase Journal of Biological Chemistry · 1997 · 124 citations
    2. Activated Polyamine Catabolism Depletes Acetyl-CoA Pools and Suppresses Prostate Tumor Growth in TRAMP Mice Journal of Biological Chemistry · 2004 · 91 citations
    3. Promotion of homology-directed DNA repair by polyamines Nature communications · 2019 · 47 citations
    4. Overexpression of spermidine/spermine N1-acetyltransferase under the control of mouse metallothionein I promoter in transgenic mice: evidence for a striking post-transcriptional regulation of transgene expression by a polyamine analogue Biochemical Journal · 1999 · 43 citations
    5. Inhibition of Polyamine Synthesis Alters Hair Follicle Function and Fiber Composition Journal of Investigative Dermatology · 1996 · 42 citations
    6. Trypanocidal Effect of Isotretinoin through the Inhibition of Polyamine and Amino Acid Transporters in Trypanosoma cruzi PLoS neglected tropical diseases · 2017 · 41 citations
    7. Polyamines and hair: a couple in search of perfection Experimental Dermatology · 2010 · 30 citations
    8. Elevated ornithine decarboxylase activity promotes skin tumorigenesis by stimulating the recruitment of bulge stem cells but not via toxic polyamine catabolic metabolites Amino Acids · 2013 · 17 citations
    9. Increased Polyamine Concentrations in the Hair of Cancer Patients Clinical chemistry · 2001 · 14 citations
    10. Overexpression of spermidine/spermine N1-acetyltransferase under the control of mouse metallothionein I promoter in transgenic mice: evidence for a striking post-transcriptional regulation of transgene expression by a polyamine analogue Biochemical Journal · 1999 · 13 citations
    11. Synthetic studies toward the development of novel minoxidil analogs and conjugates with polyamines Tetrahedron Letters · 2010 · 12 citations
    12. Increased hair polyamine levels in patients with alzheimer's disease Annals of neurology · 2001 · 10 citations
    13. Hairless and the polyamine putrescine form a negative regulatory loop in the epidermis Experimental Dermatology · 2013 · 10 citations
    14. α‐Difluoromethylornithine, a polyamine inhibitor: its potential role in controlling hair growth and in cancer treatment and chemo‐prevention International Journal of Dermatology · 2006 · 9 citations
    15. Polyamine Oxidase Expression Is Downregulated by 17β-Estradiol via Estrogen Receptor 2 in Human MCF-7 Breast Cancer Cells International Journal of Molecular Sciences · 2022 · 8 citations
    16. Commentary on: Hairless and the polyamine putrescine form a negative regulatory loop in the epidermis Experimental Dermatology · 2013 · 5 citations
    17. Altered polyamine profiling in the hair of patients with androgenic alopecia and alopecia areata Journal of Dermatology · 2019 · 4 citations
    18. Distribution of polyamines may be altered in different scalp regions of patients with hair loss Experimental Dermatology · 2019 · 3 citations
    19. Polyamine-controlled proliferation and protein biosynthesis are independent determinants of hair follicle stem cell fate bioRxiv (Cold Spring Harbor Laboratory) · 2020 · 1 citations
    20. Regulation of Hematopoietic Cell Development and Hair Growth in Mouse Models: Expression Analysis of Tudor-SN and Polyamine-Regulated Proteins Tampere University Institutional Repository (Tampere University) · 2013
    21. The remarkable legacy of the K6/ODC mouse: mechanisms of polyamine-promoted tumorigenesis revealed Amino Acids · 2026
    22. The RATIOnal Role of Polyamines in Epidermal Differentiation Journal of Investigative Dermatology · 2021
    23. 313 Different polyamine levels in the vertex and occipital hair of pattern hair loss patients Journal of Investigative Dermatology · 2019
    24. Abstract 2474: The mechanistic role of polyamines in DNA double-strand break repair Cancer Research · 2017
    25. Comparative Studies on Polyamine Levels in Plasma and Urine of Androgenic Alopecia Patients Treated with Finasteride for a Period of Three Years International Journal of Applied Biology and P · 2020
    26. Evaluation of polyamide synthetic hair. A long-term clinical study. PubMed · 2000 · 5 citations
    27. Relation of Skin Polyamines to the Hairless Phenotype in Transgenic Mice Overexpressing Spermidine/Spermine N1-Acetyltransferase Journal of Investigative Dermatology · 2001 · 54 citations
    28. Construction of conductive polyimide dressings for accelerated wound healing via an interfacial compatibility optimization and polyelectrolyte complexation synergistic strategy Chemical Engineering Journal · 2026
    29. Application of amber filler for production of novel polyamide composite fiber Textile Research Journal · 2015 · 15 citations
    30. Analysis on the Application of Polyamide (PA) materials to Replace Existing Materials in Hair Dryer Housings Highlights in Science, Engineering and Technology · 2023