Distribution of Polyamines May Be Altered in Different Scalp Regions of Patients with Hair Loss

    July 2019 in “ Experimental Dermatology ”
    Yu Ra Lee, Jeongae Lee, Bark Lynn Lew … Bong Chul Chung
    Studysummary This study reported that polyamine levels, especially N-acetyl polyamines, were higher in the vertex region of the scalp than in the occipital region in patients with male and female pattern hair loss.
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    Research cited in this study 11

    1. Differential Expression Between Human Dermal Papilla Cells from Balding and Non-Balding Scalps Reveals New Candidate Genes for Androgenetic Alopecia Journal of Investigative Dermatology · 2016
    2. N1-Methylspermidine, A Stable Spermidine Analog, Prolongs Anagen And Regulates Epithelial Stem Cell Functions In Human Hair Follicles Archives of dermatological research · 2015
    3. Regenerative Medicine and Hair Loss: How Hair Follicle Culture Has Advanced Our Understanding of Treatment Options for Androgenetic Alopecia Regenerative Medicine · 2013
    4. Commentary on: Hairless and the Polyamine Putrescine Form a Negative Regulatory Loop in the Epidermis Experimental Dermatology · 2013
    5. Hairless And The Polyamine Putrescine Form A Negative Regulatory Loop In The Epidermis Experimental Dermatology · 2013
    6. Spermidine Promotes Human Hair Growth and Is a Novel Modulator of Human Epithelial Stem Cell Functions PLOS ONE · 2011
    7. Ornithine Decarboxylase Is Upregulated by the Androgen Receptor in Skeletal Muscle and Regulates Myoblast Proliferation AJP Endocrinology and Metabolism · 2011
    8. Evaluation of Androgens in the Scalp Hair and Plasma of Patients with Male-Pattern Baldness Before and After Finasteride Administration British Journal of Dermatology · 2006
    9. Female Pattern Hair Loss Journal of The American Academy of Dermatology · 2001
    10. Modulation of Murine Hair Follicle Function by Alterations in Ornithine Decarboxylase Activity Journal of Investigative Dermatology · 1996
    11. Inhibition of Polyamine Synthesis Alters Hair Follicle Function and Fiber Composition Journal of Investigative Dermatology · 1996

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    1. Distribution of Polyamines May Be Altered in Different Scalp Regions of Patients with Hair Loss Experimental Dermatology · 2019