Polyamine-Controlled Proliferation and Protein Biosynthesis Are Independent Determinants of Hair Follicle Stem Cell Fate

    April 2020 in “ bioRxiv (Cold Spring Harbor Laboratory) ”
    Kira Allmeroth, Kim Cs, Andrea Annibal, Andromachi Pouikli, Chacón-Martínez Ca, Christian Latza, Adam Antebi, Peter Tessarz, Sara A. Wickström, Martin S. Denzel
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    Preprint — not peer reviewed. This was posted to a preprint server or data repository. It has not been through a journal's review process, and its findings may change or not hold up.

    Studysummary In this study, the researchers found that depleting natural polyamines or manipulating translation rates can enhance the stemness of hair follicle stem cells, while N1-acetylspermidine increases proliferation without affecting translation.
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