Search
for
Sort by
Research
570-600 / 1000+ results
research Oral Contraceptives and Antiandrogens Most Effective for Hirsutism Pharmacotherapy.
This meta-analysis found that combination oral contraceptive pills effectively treat hirsutism but recommends adding an antiandrogen if response is inadequate after six months.
research Simultaneous Versus Delayed Initiation of Spironolactone and Low‐Dose Oral Minoxidil: Adverse Event Rates in a Retrospective Cohort Study
This article discusses the availability of data from TriNetX for research purposes and reports no new findings.
research Comment on “Bicalutamide Improves Minoxidil-Induced Hypertrichosis in Female Pattern Hair Loss: A Retrospective Review of 35 Patients”
This study by Moussa et al. reported that bicalutamide may help reduce minoxidil-induced hypertrichosis in women with female pattern hair loss.
research Dissolving microneedles incorporating kopexil multicomponent crystals for improved transdermal delivery
This study investigated the integration of crystal engineering and microneedle technology for androgenetic alopecia treatment, finding that microneedles loaded with newly developed Kopexil multicomponent crystals reduced drug diffusion rates in vitro compared to standard formulations.
research Metformin or Antiandrogen in the Treatment of Hirsutism in Polycystic Ovary Syndrome
This study suggests that metformin may be more effective than Dianette in treating moderate to severe hirsutism in women with PCOS, while also reducing markers of insulin resistance.
research A comparison between flutamide and finasteride plus flutamide combination in the treatment of hirsutism
Flutamide alone is as effective as the combination with finasteride for treating hirsutism.
research Anti-androgenic therapy with finasteride in patients with chronic heart failure – a retrospective propensity score based analysis
In this study, anti-androgenic therapy with finasteride for prostate disease was associated with reduced cardiac hypertrophy in heart failure patients, encouraging further investigation in larger cohorts.
research Discontinuation of Alpha-Blockade after Initial Treatment with Finasteride and Doxazosin for Bladder Outlet Obstruction
This study found that patients with bladder outlet obstruction and moderately enlarged prostates are likely to successfully discontinue the a-blocker doxazosin after 9 months of combination therapy with finasteride.
research Reversible visual loss caused by combination therapy of alfuzosin and finasteride in a patient with uveitic glaucoma
This study suggests that glaucoma patients may face increased risk of optic nerve injury if prescribed medications that can lower blood pressure.
research New Progesterone Esters as 5.ALPHA.-Reductase Inhibitors.
This study found that two new progesterone derivatives showed higher antiandrogenic effects and 5α-reductase inhibition than finasteride in hamsters, particularly reducing seminal vesicle weight and flank organ size.
research Unusual presentation with polymenorrhagia and markedly high 17-hydroxy progesterone levels in a lady with Non-Classic Congenital Adrenal Hyperplasia.
This case study reports an Asian female with congenital adrenal hyperplasia presenting atypically with polymenorrhagia, who showed improvement with oral dexamethasone, despite no change in hirsutism or clitoromegaly.
research Antioxidant potential, anti-inflammatory activity, antidiabetic and cardioprotective effect of Microsechium helleri(Peyr.) Cong.
This study found that ethanolic extracts of Microsechium helleri showed notable antioxidant, hypoglycemic, and cardioprotective activities, while chloroformic extracts exhibited significant anti-inflammatory effects in experimental models.
research A case of hidradenitis suppurativa with treatment effective by finasteride
Finasteride effectively treated hidradenitis suppurativa.
research A Multi‐Center Clinical Trial to Evaluate the Efficacy of the Next Generation TriHex Technology Antiaging Regimen
This study found that using Alastin Restorative Skin Complex Serum 2.0 with TriHex Technology for 12 weeks significantly improved facial skin hydration, elasticity, and overall quality in individuals with moderate to severe skin aging, with histological evidence showing new collagen and elastin fibers.
research Trends in the prescribing pattern of spironolactone for acne and hidradenitis suppurativa in adolescents
This study reported a significant increase in the use of spironolactone for treating acne and hidradenitis suppurativa in female adolescents, noting a 2- to 3-fold rise in prescriptions and suggesting improved tolerance compared to adults, though its efficacy in adolescents is less pronounced.
research Preformulation studies of finasteride to design matrix systems for topical delivery
This study found that finasteride maintained chemical and physical stability in various excipient mixtures, which may guide the development of stable topical delivery systems.
research Agitation as a Paradoxical Effect of Divalproex Sodium: A Case Report
This case report from the University of Alabama describes a rare paradoxical effect where divalproex sodium was associated with increased agitation and hostility in a patient with schizoaffective disorder.
research Rp-HPLC Determination of Quercetin in a Novel D-α-Tocopherol Polyethylene Glycol 1000 Succinate Based SNEDDS Formulation: Pharmacokinetics in Rat Plasma
This study found that a new quercetin-loaded self-nanoemulsifying drug delivery system improved quercetin bioavailability by 149.8% compared to its suspension in rats.
research Response of Hemiballismus to Haloperidol-Reply
In this article, the author reports a case where hemiballismus was almost completely suppressed within 48 hours of starting haloperidol therapy, suggesting a therapeutic response to the drug.
research Factors influencing hydrocortisone permeation into human hair follicles: Use of the skin sandwich system
This study found that formulation factors like pH, viscosity, and chemical enhancers can significantly influence intrafollicular hydrocortisone permeation in vitro, with higher pH and enhancers reducing follicular contribution.
research Design, Synthesis, and Evaluation of Aryl Hydantoins and Ureas as Antischistosomal Agents
This study identified AH01 derivatives and related compounds with high antischistosomal efficacy and reduced antiandrogenic effects, suggesting potential new directions for schistosomiasis drug development.
research HPTLC Method Validation for simultaneous determination of Tamsulosin Hydrochloride and Finasteride in Bulk and Pharmaceutical Dosage Form
This research discusses a validated HPTLC method for simultaneously determining Tamsulosin Hydrochloride and Finasteride in bulk and pharmaceutical dosage forms but reports no new clinical results.
research Lower Urinary Tract Symptoms: What’s New in Medical Treatment?
This review discusses recent advancements and new approvals in the medical treatment of lower urinary tract symptoms, particularly highlighting drugs for nocturia and ongoing trials for multiple related conditions, while reporting no new clinical results.
research “THE EFFECT OF CYPROTERONE ACETATE AND ETHINYLESTRADIOL COMBINATION ON HYPERANDROGENIC AND OTHER SYMPTOMS IN PCOS”
This study found that combined hormonal contraceptives containing ethenyl estradiol and cyproterone acetate improved acne, hirsutism, menstrual irregularity, and dysmenorrhea in patients with polycystic ovarian syndrome, with most participants showing significant symptom improvement after 6 to 12 months.
research Hispidulin ameliorates androgenetic alopecia by inhibiting dermal papilla cell ferroptosis via TRPML1 channel activation
research FINASTERIDE (PLUS ORAL CONTRACEPTIVE PILL) VS METFORMIN IN TREATMENT OF POLYCYSTIC OVARY SYNDROME-RELATED INFERTILITY: A PROSPECTIVE RANDOMIZED TRIAL
research Thrombotic risk minimization for Diane‐35 and generics
This study observed a strong overall reduction in the use of CPA/EE in the Netherlands, despite similar proportions of users with acne or other hyperandrogenic conditions before and after the referral procedure.
research Diphenyl ethers as androgen receptor antagonists for the topical suppression of sebum production
Diphenyl ethers can potentially reduce excess oil production when applied on the skin, helping treat conditions like acne.
research Exploring the Drug-Loading and Release Ability of FucoPol Hydrogel Membranes
This study found that FucoPol hydrogel membranes can effectively deliver model drugs such as caffeine and diclofenac sodium via different loading methods, with notable mechanical and release properties, suggesting their potential as platforms for topical drug delivery.