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This study found that fluconazole increased water transport in renal cells via effects on aquaporin-2 channels, suggesting potential as a treatment for nephrogenic diabetes insipidus, though clinical trials are needed to confirm efficacy in humans.

In this study, the combination of Serenoa repens extract with Phenolmicin P3 and Bosexil suppositories significantly improved lower urinary tract symptoms and decreased PSA levels in patients with benign prostatic obstruction-related symptoms.

This study found that several synthesized compounds were potent inhibitors of human steroid 5alpha-reductase type 2 and reduced prostate weights in treated rats, with compound 15 showing promise for potency in humans.

This study found that minoxidil sulfate stimulates Cl channels, potentially depolarization-activated and outwardly rectifying, in eccrine clear cells, while minoxidil itself stimulates Ca-insensitive K currents.

Diphencyprone treatment protocols could be simplified as no harm occurred despite not fully following them.

Mitoxantrone with a corticosteroid helps manage symptoms for some advanced prostate cancer patients but doesn't extend life.

This research investigated aqueous alginate-based hydrogels for delivering minoxidil and reported that using hydroxypropyl-β-cyclodextrin (HP-β-CD) with molar substitution 0.65 significantly enhanced minoxidil's solubility and skin permeability without damaging the epidermis, suggesting potential as an alternative to commercial minoxidil solutions.

This study found that dutasteride improved maximum urinary flow rate more effectively than finasteride when used in combination therapy with tamsulosin for treating benign prostatic hyperplasia over six months.

This case series reported that three pediatric patients with hidradenitis suppurativa showed decreased frequency and severity of disease flares after treatment with oral finasteride, with no significant adverse effects.

This retrospective pharmacovigilance study reviewed adverse event reports from 2004 to 2025 for drugs treating benign prostatic hyperplasia, identifying distinct safety signals for α1-blockers, 5ARIs, and PDE5I, including some potential new adverse events that require further investigation.

In this study, spironolactone alone and combined with oral contraceptive pills significantly reduced hair shaft diameter in women with hirsutism, with the combined treatment showing the most substantial improvement.

This study found that both Finasteride and high-dose Atrazine induced hypospadias in male SD rats, establishing a reproducible animal model for this condition.

This review reports very low quality evidence for the effectiveness and safety of treatments in extensive resistant alopecia areata and emphasizes the need for high-quality randomized controlled trials.

This study reports that sacituzumab govitecan achieved a 33.3% overall response rate in patients with metastatic triple-negative breast cancer who had prior treatments, with a median response duration of 7.7 months.

This case report identified trichorrhexis nodosa in a patient, likely due to the topical use of an ayurvedic preparation containing calcium hydronide.

This case report from the University of Alabama, Birmingham describes a rare paradoxical reaction of increased agitation and hyperactivity in a patient with schizoaffective disorder treated with divalproex sodium.

In these two clinical trials, DS-2325a, a KLK5 inhibitor, was found to be generally safe and well tolerated in healthy volunteers, with mild and non-serious adverse events, suggesting its potential for further development as a treatment for Netherton Syndrome.

Combination therapy improves urinary flow and reduces residual urine, but needs better stent design.

This review summarizes recent advancements in steroidal 5α-reductase inhibitors for benign prostatic hyperplasia and reports no new clinical results.

This study observed that cyclosporine, an immunosuppressive drug used in renal transplantation, can cause temporary hypertrichosis, with patients experiencing significant hair loss after discontinuing the medication.

This study found that using nanoporous silica entrapped lipid-drug complexes enhanced the solubility and bioavailability of dutasteride in beagle dogs.

This study found that long-term use of difluprednate ophthalmic emulsion in dogs can lead to HPA axis suppression and potentially cause iatrogenic hyperadrenocorticism, with localized alopecia suspected due to dermal absorption.

This review found that finasteride monotherapy for managing LUTS/BPH significantly reduced prostate volume and improved symptoms, with sexual dysfunctions reported as notable side effects compared to placebo, but emphasizes the need for more comprehensive studies.

This study found that plasma 3 alpha-diol glucuronide was markedly elevated in women with idiopathic hirsutism, suggesting it may be a marker of peripheral androgen action.

This case study reported that even with improved adrenal androgens and testosterone levels, treating women with AH-PCOS with glucocorticoids did not significantly improve ovulatory function or hirsutism.

This study found that an 8-month treatment with a low-dose oral contraceptive significantly reduced testosterone levels and hair growth in women with polycystic ovary syndrome and hirsutism, with minimal side effects.

This study explored the effects of a 50% hydroalcoholic UPBF extract on BPH in testosterone propionate-induced rats, finding significant improvements in prostate-related parameters and lower urinary tract symptoms at a 200 mg/kg dose, suggesting potential use in BPH management.

This randomized controlled study reported that combining Ecklonia cava with Diane-35 significantly improved weight, waist circumference, hormonal balance, and inflammation markers in women with polycystic ovary syndrome over three months compared to Diane-35 alone.

In this study, researchers developed a dexpanthenol-infused nanotechnological platform within hyaluronic acid hydrogels that promoted wound healing in mice by providing a protective barrier and significantly enhancing skin regeneration, including increased fibroblast activity and tissue remodeling.