Comparison of Combination Therapy With Tamsulosin and Dutasteride or Finasteride in Patients With Benign Prostatic Hyperplasia: A Randomized Clinical Trial

September 2024 in “ African Journal of Urology ”

Abbas Basiri, Rasool Zare, Mazyar Zahir, Amir Hossein Kashi, Mahsa Zobeiry, Nasrin Borumandnia, Amir Reza Abedi, Shabnam Golshan

dutasteride finasteride tamsulosin benign prostatic hyperplasia BPH International Prostate Symptom Score IPSS prostate specific antigen PSA Avodart Propecia Flomax

From the encyclopedia

Dutasteride →

Heavy duty finasteride that comes with higher risks

Finasteride →

Frontline, gold standard treatment for combatting androgenic alopecia

tamsulosin →

Studysummary This study found that dutasteride improved maximum urinary flow rate more effectively than finasteride when used in combination therapy with tamsulosin for treating benign prostatic hyperplasia over six months.

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Research cited in this study

4 / 4 results

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13 citations , February 2022 in “JAMA Dermatology”

This meta-analysis reported that 0.5 mg/d of dutasteride significantly increased total hair count at 24 weeks compared to finasteride and minoxidil in men with androgenetic alopecia.

Change in Prostate-Specific Antigen Concentration in Men with Prostate-Specific Antigen Less Than 2.5 ng/mL Taking Low-Dose Finasteride or Dutasteride for Male Androgenetic Alopecia

research Change in Prostate-Specific Antigen Concentration in Men with Prostate-Specific Antigen Less Than 2.5 ng/mL Taking Low-Dose Finasteride or Dutasteride for Male Androgenetic Alopecia

1 citations , July 2017 in “The Journal of Urology”

In this study, low dose finasteride or dutasteride treatment was found to reduce prostate specific antigen levels in men with androgenetic alopecia, though levels sometimes remained stable or increased in those with low baseline PSA.

research The Efficacy of Terazosin, Finasteride, or Both in Benign Prostatic Hyperplasia

728 citations , August 1996 in “The New England Journal of Medicine”

Terazosin and finasteride effectively treat BPH, but combining them adds no extra benefit.

research The Effect of Finasteride in Men with Benign Prostatic Hyperplasia

1040 citations , October 1992 in “The New England Journal of Medicine”

In this study, 5 mg of finasteride per day significantly improved urinary symptoms and reduced prostate volume in men with benign prostatic hyperplasia, but increased the risk of sexual dysfunction.