Diphenylcyclopropenone in Patients with Alopecia Areata: A Critically Appraised Topic

October 2015 in “ British Journal of Dermatology ”

Rosanna A. Kuin, Phyllis I. Spuls, Jacqueline Limpens, Esther J van Zuuren

TLDR Diphenylcyclopropenone's effectiveness and safety for alopecia areata are unclear.

The document concluded that there was very low quality evidence supporting the effectiveness and safety of diphenylcyclopropenone in treating extensive resistant alopecia areata. It emphasized the need for well-designed and well-conducted randomized controlled trials with comprehensive reporting and high-quality methodological descriptions to better assess the treatment's efficacy and safety.

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Research cited in this study

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DPCP is more effective than tretinoin gel for treating severe alopecia.

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