A Double-Blind, Randomized, Placebo-Controlled Pilot Study to Investigate the Effects of Finasteride Combined with a Biodegradable Self-Reinforced Poly L-Lactic Acid Spiral Stent in Patients with Urinary Retention Caused by Bladder Outlet Obstruction

July 2001 in “ BJUI ”

T. Isotalo, Martti Talja, Pekka Hellström, Ilkka Perttilä, Tero Välimaa, Pertti Törmälä, Teuvo L.J. Tammela

TLDR Combination therapy improves urinary flow and reduces residual urine, but needs better stent design.

The study investigated the effects of combining finasteride with a biodegradable stent in patients with urinary retention caused by bladder outlet obstruction. The combination therapy was found to be effective in improving urinary flow rate and reducing residual urine volume compared to placebo, but there were issues with treatment discontinuation and stent breakdown. New stent configurations are needed to improve the treatment's effectiveness.

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Research cited in this study

2 / 2 results

The Effect of Finasteride on the Risk of Acute Urinary Retention and the Need for Surgical Treatment Among Men with Benign Prostatic Hyperplasia

research The Effect of Finasteride on the Risk of Acute Urinary Retention and the Need for Surgical Treatment Among Men with Benign Prostatic Hyperplasia

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A Double-Blind, Randomized, Placebo-Controlled Pilot Study to Investigate the Effects of Finasteride Combined with a Biodegradable Self-Reinforced Poly L-Lactic Acid Spiral Stent in Patients with Urinary Retention Caused by Bladder Outlet Obstruction

Research cited in this study

research The Effect of Finasteride on the Risk of Acute Urinary Retention and the Need for Surgical Treatment Among Men with Benign Prostatic Hyperplasia

research The Effect of Finasteride in Men with Benign Prostatic Hyperplasia

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