TLDR Combination therapy improves urinary flow and reduces residual urine, but needs better stent design.
The study investigated the effects of combining finasteride with a biodegradable stent in patients with urinary retention caused by bladder outlet obstruction. The combination therapy was found to be effective in improving urinary flow rate and reducing residual urine volume compared to placebo, but there were issues with treatment discontinuation and stent breakdown. New stent configurations are needed to improve the treatment's effectiveness.
1054 citations
,
February 1998 in “The New England Journal of Medicine” Finasteride reduces urinary issues and surgery need in men with enlarged prostates by over 50%.
1040 citations
,
October 1992 in “The New England Journal of Medicine” Finasteride effectively treats BPH but may increase sexual dysfunction risk.
11 citations
,
February 2004 in “Clinical and Experimental Ophthalmology” Taking Propecia might lead to the development of cataracts.
June 2024 in “Georgetown medical review” Finasteride treats hair loss but may cause low libido, erectile issues, and depression.
June 2017 in “Reactions Weekly” Finasteride (Propecia) may cause depression and suicidal thoughts; stop use and inform a healthcare professional if symptoms develop.
3 citations
,
June 2004 in “Annales De Dermatologie Et De Venereologie” Four new cases of gynecomastia (male breast enlargement) linked to finasteride (Propecia) have been found.
2 citations
,
January 2003 in “Journal of Clinical Dermatology” 1 mg finasteride can cause reversible painful breast enlargement in men.
April 2012 in “Reactions Weekly” Finasteride may cause more sexual side effects than previously thought.