Efficacy and Safety of Finasteride Monotherapy in Patients with Benign Prostatic Hyperplasia: A Critical Review of the Literature

    January 2020 in “ Archivio Italiano di Urologia e Andrologia ”
    Gian Maria Busetto, Francesco Del Giudice, Daniele D’Agostino … Angelo Porreca
    Studysummary This review found that finasteride monotherapy for managing LUTS/BPH significantly reduced prostate volume and improved symptoms, with sexual dysfunctions reported as notable side effects compared to placebo, but emphasizes the need for more comprehensive studies.
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    Research cited in this study 10

    1. Risk of Depression After 5 Alpha Reductase Inhibitor Medication: Meta-Analysis The World Journal of Men's Health · 2019
    2. Efficacy and Safety of 5 Alpha-Reductase Inhibitor Monotherapy in Patients with Benign Prostatic Hyperplasia: A Meta-Analysis PLOS ONE · 2018
    3. Adverse Sexual Effects of Treatment with Finasteride or Dutasteride for Male Androgenetic Alopecia: A Systematic Review and Meta-Analysis Acta dermato-venereologica · 2018
    4. Current Pharmacological Treatment for Male LUTS Due to BPH: Dutasteride or Finasteride? Current Drug Targets · 2015
    5. Depressive Symptoms and Suicidal Thoughts Among Former Users of Finasteride With Persistent Sexual Side Effects The Journal of Clinical Psychiatry · 2012
    6. Persistent Sexual Side Effects of Finasteride: Could They Be Permanent? The Journal of Sexual Medicine · 2012
    7. Promising Therapies for Treating and Preventing Androgenic Alopecia PubMed · 2012
    8. The Long-Term Effect of Doxazosin, Finasteride, and Combination Therapy on the Clinical Progression of Benign Prostatic Hyperplasia The New England Journal of Medicine · 2003
    9. Effects of Finasteride on Vascular Endothelial Growth Factor Scandinavian Journal of Urology and Nephrology · 2002
    10. The Effect of Finasteride in Men with Benign Prostatic Hyperplasia The New England Journal of Medicine · 1992

    Related research 2

    1. Comparative Effect of Finasteride and Dutasteride on Chromogranin A Levels Anticancer Research · 2010
    2. Comparison of Clinical Trials with Finasteride and Dutasteride PubMed · 2004