Reversible Visual Loss Caused by Combination Therapy of Alfuzosin and Finasteride in a Patient with Uveitic Glaucoma

June 2013 in “ Cutaneous and Ocular Toxicology ”

Jong Wook Lee, Hyun Lee

finasteride alfuzosin tamsulosin benign prostatic hyperplasia uveitic glaucoma Propecia Flomax

TLDR Taking alfuzosin and finasteride together caused temporary vision loss in a glaucoma patient, but switching to tamsulosin helped.

A 60-year-old man with uveitic glaucoma experienced reversible visual loss after taking a combination regimen of alfuzosin and finasteride for benign prostatic hyperplasia (BPH). The patient's symptoms improved after the medication was changed to tamsulosin monotherapy. The authors suggest that drugs that can cause systemic hypotension should be prescribed with caution to glaucoma patients.

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Research cited in this study

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research The Long-Term Effect of Doxazosin, Finasteride, and Combination Therapy on the Clinical Progression of Benign Prostatic Hyperplasia

1707 citations, December 2003 in “The New England Journal of Medicine”

Combination therapy of doxazosin and finasteride safely and effectively reduces benign prostatic hyperplasia progression risk.

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research Reversible Visual Loss Caused by Combination Therapy of Alfuzosin and Finasteride in a Patient with Uveitic Glaucoma

2 citations, June 2013 in “Cutaneous and Ocular Toxicology”

Taking alfuzosin and finasteride together caused temporary vision loss in a glaucoma patient, but switching to tamsulosin helped.