26 citations
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January 1992 in “Cancer investigation” This study found that N-acetylcysteine effectively prevented cyclophosphamide-induced alopecia in rats, and ImuVert plus N-acetylcysteine prevented alopecia from a cyclophosphamide-cytarabine combination.
13 citations
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June 2018 in “Journal of Womens Health” This study found that in women with PCOS, suppressive therapy using spironolactone plus oral contraceptives improved hirsutism more effectively than either treatment alone, with initial scores predicting success.
6 citations
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July 2016 in “Doklady Biochemistry and Biophysics” This study found that GD-23, a dipeptide ligand of TSPO, exhibited an anxiolytic effect in the elevated plus maze test, which was inhibited by selective neurosteroid synthesis inhibitors, suggesting a neurosteroidogenic mechanism.
September 2023 in “Journal of the American Academy of Dermatology” In this study, a cosmetic product with nano encapsulated cysteamine plus sunscreen significantly improved melasma symptoms and quality of life in adult women over 84 days, compared to sunscreen alone, without any medically relevant intolerance.
July 2021 in “Indian Journal of Animal Research” This study reports that among rats with penile fractures, those treated with primary repair plus homologous platelet-rich plasma showed the best healing compared to other treatment methods.
January 2009 in “Journal watch” This study enrolled nine patients to investigate the effects of oral psoralen and ultraviolet A therapy plus oral prednisolone for treating alopecia areata.
January 2009 in “Academic Journal of Second Military Medical University” In this study, adolescent male acne patients with normal serum testosterone showed improved outcomes with finasteride plus lifestyle intervention, significantly reducing DHT and free testosterone levels and improving SHBG levels, with minimal adverse effects.
January 2006 in “Zhongguo yaofang” This study concluded that qianliekang combined with liuweidihuangwan is a more economical treatment for benign prostatic hyperplasia compared to finasteride plus tamsulosin.
March 2023 in “Aktualʹnì pitannâ farmacevtičnoï ì medičnoï nauki ta praktiki” This study found that a 2% minoxidil cream and a gel-based shampoo with 1% minoxidil plus plant extracts showed significant hair growth and follicle-protective effects in laboratory rats with experimental alopecia.
1 citations
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January 2001 This article discusses surgical hair restoration using micrografting techniques, emphasizing its ability to produce natural-looking results without the "hair plug" appearance, and reports no new clinical findings.
68 citations
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February 2015 in “Journal of the European Academy of Dermatology and Venereology” This study found that severe folliculitis decalvans was associated with its onset before age 25 and the presence of pustules, while tetracyclines and clindamycin plus rifampicin were effective treatments.
58 citations
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November 2018 in “Cochrane library” This study found that oral isotretinoin may slightly improve physician-assessed acne severity but is associated with more minor adverse effects compared to standard oral antibiotics plus topical treatment, based on low-quality evidence.
39 citations
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November 2016 in “Pharmaceutics” This study found that the contribution of the hair follicle pathway to skin permeation of chemicals can be predicted using lipophilicity, with hydrophilic chemicals showing greater permeation reduction from hair follicle plugging than lipophilic ones.
21 citations
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November 2017 in “Cochrane library” This study concluded that laparoscopic ovarian drilling does not clearly improve menstrual regularity or androgenic symptoms in PCOS compared to most medical treatments, but it may have fewer gastrointestinal side effects than metformin plus clomiphene.
12 citations
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March 2019 in “Cosmetics” In this study, a combined regimen of an oral supplement with Pinus pinaster, Grape seed extract, vitamins, and minerals, plus high SPF sunscreen, significantly improved mild-to-moderate facial melasma in 30 women over 84 days, reducing pigmentation and enhancing cosmetic appearance with no reported adverse effects.
6 citations
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December 2015 in “International journal of nanomedicine” This study found that low-frequency sonophoresis significantly decreased the skin penetration of sodium fluorescein-loaded PEGylated liposomes with D-limonene and affected percutaneous absorption by partially plugging hair follicle orifices.
4 citations
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June 2016 in “Rossiiskii Zhurnal Kozhnykh i Venericheskikh Boleznei” This study describes a clinical investigation of telogen effluvium with iron deficiency anemia, comparing treatment with Fe2+ salts alone to Fe2+ salts plus topical Qilib, but reports no new results.
3 citations
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March 2021 in “Metabolites” This study identified distinct differences in metabolic pathways related to pattern baldness, with findings highlighting the androgen metabolic pathway in males and the estrogen plus arachidonic acid pathways in females using hair samples.
3 citations
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April 2015 in “International research journal of pharmacy” This study concluded that the follicular route is a significant pathway for delivering gentamicin through the skin, as demonstrated by higher drug permeation in non-plugged pig's ear skin compared to plugged skin.
3 citations
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July 1993 in “Contraception” In this study, elevated prolactin and DHEA-S levels along with reduced SBP were observed in fertile non-obese women with moderate body hair compared to controls, and ethynylestradiol plus desogestrel or cyproterone acetate treatment improved clinical outcomes by increasing SBP.
1 citations
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August 2013 in “Facial Plastic Surgery Clinics of North America” This article reviews the evolution and advancements in hair restoration techniques over the past 20 years, emphasizing the shift from "plug" methods to natural-looking follicular unit grafts, but reports no new experimental results.
July 2026 in “Journal of Cosmetic Dermatology” This network meta-analysis found that for female pattern hair loss, microneedling combined with minoxidil ranked highest for hair density and patient satisfaction, while poly-L-lactic acid threads plus minoxidil led in hair diameter; however, the evidence is uncertain and lacks placebo-controlled trials.
December 2025 in “Drug Design Development and Therapy” This retrospective study reported that in HER-2-negative metastatic breast cancer patients, anlotinib combined with taxane/capecitabine showed superior disease control rate, progression-free survival, and overall survival compared to bevacizumab plus chemotherapy, with both treatments having tolerable safety profiles.
July 2025 in “Buletin Veteriner Udayana” This study reports a case of generalized dermatitis in a mixed-breed German Spitz due to Sarcoptes scabiei and Malassezia sp. infection, treated with ivermectin and fluconazole, plus supportive therapies, resulting in marked lesion reduction though not full recovery.
June 2017 in “Poster presentations” In this study, the safety profiles of four treatments for early rheumatoid arthritis were assessed over one year, and the most serious side effects necessitating treatment discontinuation were noted in the leflunomide group, whereas no such withdrawals occurred in the methotrexate plus prednisolone group.
February 2006 in “PubMed” In this study, docetaxel combined with prednisone significantly extended survival by about 2.5 months in men with hormone-resistant metastatic prostate cancer compared to mitoxantrone plus prednisone, despite the potential for severe adverse effects.
1 citations
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April 1995 in “Annals of Plastic Surgery” This study describes the Mercedes incision technique, which may improve hair transplant results by reducing graft compression and row cropping, leading to a more natural appearance.
August 2015 in “Evidence Based Women Health Journal (Online)” This study found that inositol was significantly more effective than Metformin in promoting weight reduction, spontaneous ovulation, and pregnancy in patients with polycystic ovary syndrome.
57 citations
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October 1996 in “Dermatologic clinics” This study found that using hyaluronic acid microneedles to deliver minoxidil significantly reduced hair loss in chemotherapy-induced alopecia mice, with only 10% of the dose used in topical applications.
22 citations
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November 2002 in “Clinical journal of oncology nursing” This article discusses arsenic trioxide as a treatment for refractory or relapsed acute promyelocytic leukemia, noting its effectiveness and manageable side effects.