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In this study using mice and human keratinocyte cells, researchers found that activating PKM2-mediated glycolysis and Wnt/β-catenin signaling, particularly via combined treatments, significantly accelerated wound healing and induced angiogenesis in wound beds.

This study found that activating both PKM2 and Wnt/β-catenin signaling pathways significantly enhanced hair regrowth and hair follicle neogenesis in mice, suggesting a potential strategy for treating alopecia.

This study found that activating PKM2 and Wnt/β-catenin signaling enhanced hair regrowth and hair follicle stem cell proliferation in mice, suggesting a potential alopecia treatment strategy.

This study identified specific lncRNAs and mRNAs differentially expressed in miniaturized follicles compared to normal follicles in patients with androgenetic alopecia, with AL136131.3 potentially inhibiting hair growth and accelerating follicle transition to catagen through effects on glycolysis-related genes.

This study found that activating both PKM2 and Wnt/β-catenin signaling enhanced hair re-growth and HFSCs proliferation in mice, suggesting a potential treatment strategy for alopecia.

This study found that overexpression of the lncRNA AL136131.3 may inhibit hair shaft growth and promote hair follicle apoptosis in androgenetic alopecia by influencing key metabolic pathways.

This review discusses the multifunctional role of PKM2 in promoting cardiac repair and regeneration, highlighting its potential as a therapeutic target in cardiovascular medicine, but reports no new experimental results.

This review discusses the potential of targeting Coenzyme A metabolism to restore metabolic balance, reduce chronic inflammation, and enhance immune function, particularly by modulating Vitamin B5 pathways involved in Th17-mediated inflammation and CD8-dependent anti-tumor immunity.

In this community service project, the researchers found that educating the public about using clove leaves as a herbal remedy for hair growth issues in Indonesia significantly increased public knowledge from 17.91% to 45.86%.

This article describes community efforts to increase awareness and effective utilization of guava plant resources in Pamulang, aiming to improve local economic welfare through better cultivation practices and innovative processing of guava for health benefits.

This study found that a 15% Pisum sativum extract concentration in hair tonic showed the most effective hair growth, with a length of 14.51mm and weight of 0.16g.

This study found that MOOEW Hair Tonic had a Return of Investment of over 100%, indicating significant potential for profitable and sustainable business opportunities.

This study involved educating Dewantara Husada Health Vocational High School students about using meniran leaf extract in pomade formulations as a hair growth stimulant, demonstrating high engagement and interest in the topic.

This study observed that disrupting the Pnkp gene in adult mice resulted in a premature aging-like phenotype, suggesting PNKP's vital role in maintaining normal growth and survival of certain progenitor cell populations.

This study found multipotent progenitors in sweat ducts that become unipotent after sweat gland development, highlighting distinct regenerative capabilities in adult glandular skin stem cell populations.

This study found that glycolytic metabolism and lactate production are crucial for hair follicle stem cell activation, and manipulating these processes can stimulate the hair cycle.

This study found that expressing certain PIN proteins in Arabidopsis root hairs inhibited growth by decreasing auxin levels, while PIN5 slightly stimulated growth, demonstrating differential effects on auxin transport.

This review discusses the role of phytochemical nanoparticles in cervical cancer therapy and reports no new clinical results; the authors highlight their potential advantages over conventional chemotherapy.

This study found that vitamin C increased the survival, proliferation, and hair-regenerative potential of adipose-derived stem cells through the MAPK pathway and enhanced hair growth in mice.

This study found that deleting Stim1 and Stim2 in mature T regulatory cells disrupts Ca 2+ signaling, preventing their differentiation and leading to severe autoimmune disorders in mice.

This study found that Ldh activity in hair follicle stem cell-mediated squamous cell carcinoma is not necessary for tumorigenesis, as its modulation did not affect the cancer's development or characteristics.

This review highlights the potential of natural product-derived compounds, such as flavonoids and alkaloids, to reverse multidrug resistance in tumors, emphasizing their role in regulating signaling pathways, proteins, and genes related to MDR, and aims to guide future research efforts in this area.

This review discusses how epidermal Langerhan's cells and dermal cells may influence keratinocyte environments, potentially aiding in the formation of stem cell niches and cellular variety in the basal layer, without providing novel results.

This study found that DHT treatment led to reduced cell growth, increased cell death, cell cycle arrest, ROS production, and senescence in normal human dermal papilla cells, potentially mediated by altered miRNA expression.

This study provided the first proteome dataset for alopecia areata, revealing novel pathways in the disease mechanisms that may lead to new therapeutic targets.

The researchers reported that hair follicle germinative epidermal cells can form complex structures when associating with papilla cells in culture, unlike other types of epidermal cells.

This study found that UVB radiation significantly alters miRNA expression and induces cytotoxicity and apoptosis in normal human dermal papilla cells.

This study found that platelet-rich plasma may influence the proliferation of human hair dermal papilla cells by affecting gene expression related to the cell cycle.

This study concludes that egg shell membrane hydrolysates, particularly Fraction I, may effectively mitigate UV-B radiation-induced wrinkles and promote skin collagen and hyaluronic acid production, suggesting potential use in functional cosmetics.

In this study, transcriptome analysis identified 68 differentially expressed miRNAs in human dermal papilla cells treated with hydrogen peroxide, suggesting they play a significant role in growth arrest and apoptosis.