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    Research 30 of 502

    1. Wedelolactone, a medicinal plant-derived coumestan, induces caspase-dependent apoptosis in prostate cancer cells via downregulation of PKCε without inhibiting Akt International Journal of Oncology · 2012 · 83 citations
    2. Interleukin-1β Is Differentially Expressed by Human Dermal Papilla Cells in Response to PKC Activation and Is a Potent Inhibitor of Human Hair Follicle Growth in Organ Culture Journal of interferon & cytokine research · 1997 · 38 citations
    3. Two Mechanisms Regulate Keratin K15 Expression In Keratinocytes: Role of PKC/AP-1 and FOXM1 Mediated Signalling PloS one · 2012 · 35 citations
    4. PKC downregulation upon rapamycin treatment attenuates mitochondrial disease Nature metabolism · 2020 · 26 citations
    5. Genetic deletion of TNFα inhibits ultraviolet radiation-induced development of cutaneous squamous cell carcinomas in PKCε transgenic mice via inhibition of cell survival signals Carcinogenesis · 2015 · 11 citations
    6. PKCδ/MAPKs and NF-κB Pathways are Involved in the Regulation of Ingenane-Type Diterpenoids from Euphorbia neriifolia on Macrophage Function Journal of Inflammation Research · 2021 · 9 citations
    7. Pharmacological investigation of vitamin E with combined oral contraceptives on INHBA gene against PCOS that intricate through melatonin PKC pathway Systems Biology in Reproductive Medicine · 2023
    8. CD271 orchestrates skin structure, differentiation, and inflammation via PI3K/Akt and PKCα/ERK pathways Cell Death and Disease · 2025
    9. 477 Dietary fat- and obesity-sensitive dermal adipocyte PKCβ induction and inflammation cross-talk Journal of Investigative Dermatology · 2017
    10. 441 RPGRIP1L facilitates desmosomal adhesion through suppressing PKCβII-mediated desmoglein endocytosis: Implication in pemphigus 2016
    11. Regulation of Involucrin Gene Expression Journal of Investigative Dermatology · 2004 · 138 citations
    12. Corticotropin releasing hormone and the skin Frontiers in bioscience · 2006 · 137 citations
    13. Overexpression of protein kinase C-α in the epidermis of transgenic mice results in striking alterations in phorbol ester-induced inflammation and COX-2, MIP-2 and TNF-α expression but not tumor promotion Journal of Cell Science · 1999 · 135 citations
    14. Transgenic mice overexpressing protein kinase C epsilon in their epidermis exhibit reduced papilloma burden but enhanced carcinoma formation after tumor promotion. PubMed · 2000 · 99 citations
    15. Self-organization process in newborn skin organoid formation inspires strategy to restore hair regeneration of adult cells Proceedings of the National Academy of Sciences of the United States of America · 2017 · 92 citations
    16. Keratin K15 as a Biomarker of Epidermal Stem Cells International Journal of Molecular Sciences · 2013 · 85 citations
    17. Bone morphogenetic protein-2 (BMP-2) transactivates Dlx3 through Smad1 and Smad4: alternative mode for Dlx3 induction in mouse keratinocytes Nucleic Acids Research · 2002 · 79 citations
    18. Protein kinase Cepsilon is linked to 12-O-tetradecanoylphorbol-13-acetate-induced tumor necrosis factor-alpha ectodomain shedding and the development of metastatic squamous cell carcinoma in protein kinase Cepsilon transgenic mice. PubMed · 2003 · 79 citations
    19. Protein Kinase Cε, which Sensitizes Skin to Sun's UV Radiation–Induced Cutaneous Damage and Development of Squamous Cell Carcinomas, Associates with Stat3 Cancer Research · 2007 · 76 citations
    20. Activation of Cutaneous Protein Kinase Cα Induces Keratinocyte Apoptosis and Intraepidermal Inflammation by Independent Signaling Pathways The Journal of Immunology · 2003 · 74 citations
    21. Two distinct signaling pathways in hair cycle induction: Stat3-dependent and -independent pathways Proceedings of the National Academy of Sciences of the United States of America · 2000 · 73 citations
    22. Inducible Cutaneous Inflammation Reveals a Protumorigenic Role for Keratinocyte CXCR2 in Skin Carcinogenesis Cancer Research · 2008 · 70 citations
    23. Topical Application of a Protein Kinase C Inhibitor Reduces Skin and Hair Pigmentation 2004 · 60 citations
    24. Cyclosporin A Promotes Hair Epithelial Cell Proliferation and Modulates Protein Kinase C Expression and Translocation in Hair Epithelial Cells Journal of Investigative Dermatology · 2001 · 45 citations
    25. Procyanidin B-2, extracted from apples, promotes hair growth: a laboratory study 2002 · 37 citations
    26. Protein Kinase C δ Overexpressing Transgenic Mice Are Resistant to Chemically but not to UV Radiation–Induced Development of Squamous Cell Carcinomas: A Possible Link to Specific Cytokines and Cyclooxygenase-2 Cancer Research · 2006 · 35 citations
    27. Several Selective Protein Kinase C Inhibitors Including Procyanidins Promote Hair Growth Skin pharmacology and physiology · 2000 · 32 citations
    28. Androgens Induce Nongenomic Stimulation of Colonic Contractile Activity through Induction of Calcium Sensitization and Phosphorylation of LC20 and CPI-17 Molecular Endocrinology · 2010 · 31 citations
    29. Protein Kinase C Epsilon Signals Ultraviolet Light-induced Cutaneous Damage and Development of Squamous Cell Carcinoma Possibly Through Induction of Specific Cytokines in a Paracrine Mechanism¶ Photochemistry and Photobiology · 2005 · 28 citations
    30. Foxn1 promotes keratinocyte differentiation by regulating the activity of protein kinase C Differentiation · 2007 · 26 citations