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Single Blimp1+ cells can create functional sebaceous gland organoids in the lab.

Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.

The arrector pili muscle might play a role in hair loss and needs more research to understand its impact.

Acne is common in women, often hormone-related, negatively affects quality of life, and requires various treatments.

Androgen receptor signaling causes early aging of cells important for hair growth by damaging their DNA.

Fully regenerating human hair follicles not yet achieved.

Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.

New lipid nanoparticles show promise for delivering hair loss treatments but need improvement for better skin penetration.

Oleic acid nanovesicles improve minoxidil absorption in hair follicles for alopecia treatment.

Male faces age with more wrinkles and hair loss, influenced by both body changes and environmental factors.

Birth control pills combined with bicalutamide are more effective at reducing excessive hair growth in women with PCOS than birth control pills alone.

Microneedling helps increase the absorption of a melanin product into hair follicles, which may improve laser hair removal effectiveness.

Acne severity in women may not be linked to increased male hormone indicators like excess body hair, menstrual irregularities, or hair loss.

DHT stops hair regrowth in mice, similar to human hair loss.

HPV16 oncogenes disrupt the normal activity of hair follicle stem cells.

Ethosomal minoxidil improves hair growth by penetrating deeper into skin and shortening hair cycle.

Hair restoration surgery techniques have evolved, with focus on patient selection and realistic goals, and future advancements may include cloning and gene therapy.

Topical DPCP is somewhat effective for hair loss in alopecia areata, but more research is needed.

Telogen is an active phase with important biological processes, not a resting phase.

The document concludes that various drugs can manage symptoms and metabolic issues in women with PCOS.

Male hormones indirectly affect skin cell development by increasing growth factor levels from skin fibroblasts.

Hair gets thinner, grayer, and changes texture with age due to genetics, environment, and cellular changes, affecting the growth cycle.

Liposomes can make the antiandrogen RU 58841 more effective for skin application by reducing absorption, increasing skin retention, and targeting sebaceous structures.

Isotretinoin improves severe acne without changing androgen or insulin levels but may increase body weight and triglycerides.

The Nd:YAG laser safely reduces facial hair and slows regrowth, with patient satisfaction.

Androgen excess disorders in women were effectively treated with spironolactone, estrogen, and dexamethasone.

Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.

The article concludes that hair loss is a common side effect of drugs treating skin cancer by blocking the hedgehog pathway, but treatment should continue, and more selective drugs might prevent this side effect.

Researchers developed a nanomedicine for acne treatment that delivers medication with less irritation and is non-irritating for oily skin.

Obese women had more testosterone and less acne, but similar hair growth compared to non-obese women.